Reducing Lung Cancer Risk for Appalachian Women with Community-Driven Help
Official title: Reducing Lung Cancer Risk among Appalachian Women Using Community‐Engaged Intervention Research
Funded at Pennsylvania State University, the · NIH-11418164 · Data updated 2026-11-12
A community-informed program aims to lower lung cancer risk among Appalachian women by testing a behavior-focused intervention tailored to local social and environmental contexts.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Pennsylvania State University, the NIH-funded |
| Lab location | 1 site (University Park, United States) |
| Project start | May 1, 2024 |
| Project end | April 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $236,223 |
| NIH project number | 5R00CA277245-05 |
| Project ID | NIH-11418164 on NIH RePORTER |
Who could benefit from this research
✓Could help
Appalachian women who are at risk for lung cancer and are able to participate in a community-engaged behavioral trial.
✕Less likely to help
Women who cannot participate in a behavioral trial (e.g., due to location, time constraints, or health conditions) may not benefit from this intervention.
What this research studies
This project adapts and pilots a behavioral intervention for Appalachian women to reduce lung cancer risk, guided by community input. It uses a two-armed randomized trial to test feasibility, acceptability, and implementation of the adapted program. The work builds on prior K99 findings and preserves a community-engaged approach throughout development and testing. The goal is to create an intervention that fits local realities and can be feasibly brought into practice in the Appalachian region.
Why it matters
Potential benefit: If successful, the intervention could reduce lung cancer risk factors and improve health outcomes for women in Appalachia.
How similar studies have gone: Prior phases have shown that community-engaged, multilevel approaches are feasible and acceptable in this population, with pilot testing guiding adaptation.
Where this research is happening
-
Pennsylvania State University, the
University Park, United States Active
Researchers
- Principal investigator: Thompson, Jessica Ruth — Pennsylvania State University, the
- Study coordinator: Thompson, Jessica Ruth
Related research
Other NIH-funded projects on the same topics.
-
Blood-based markers to identify lung cancer risk in never-smokers
A researchers team at NYU School of Medicine is testing blood tests that might flag higher lung cancer risk in people who have never smoked, helping decide who might need screening.
-
Integrative Analysis of Lung Cancer Risk and Its Causes
A large, multi-part study at the University of New Mexico is exploring why lung cancer happens and how to better prevent and detect it.
-
Integrative Analysis of Lung Cancer Risk and Causes
A large NIH project is exploring how tobacco use, behavior, biology, and screening practices influence lung cancer risk and outcomes to help prevent and detect it earlier.
-
Digital health strategies to expand lung cancer screening in safety-net clinics
A funded project aims to help low-resource clinics increase the use of lung cancer screening for patients who smoke or are at risk.
-
Proteomics-guided matching of lung cancer tumors to preclinical models
This grant aims to improve how we match a patient’s lung cancer tumor to the right preclinical models using protein data.
-
Optimizing lung cancer care with smart tools for prevention, early detection, treatment, and survivorship
A U01 grant using AI and biomarkers to improve lung cancer prevention, screening, treatment, and survivorship care for people at risk or living with lung cancer.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.