Integrative Analysis of Lung Cancer Risk and Its Causes
Official title: Integrative Analysis of Lung Cancer Etiology and Risk
Funded at University of New Mexico Health Scis Ctr · NIH-11523887 · Data updated 2026-11-12
A large, multi-part study at the University of New Mexico is exploring why lung cancer happens and how to better prevent and detect it.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of New Mexico Health Scis Ctr NIH-funded |
| Lab location | 1 site (Albuquerque, United States) |
| Project start | August 1, 2017 |
| Project end | March 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $500,555 |
| NIH project number | 3U19CA203654-10S2 |
| Project ID | NIH-11523887 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates include adults at risk for or with early signs of lung cancer, particularly those who smoke or have a history of tobacco exposure and who are eligible for screening programs.
✕Less likely to help
Individuals without lung cancer risk factors or those not participating in screening programs may not directly benefit.
What this research studies
This project looks at how smoking and other behaviors contribute to lung cancer and how to improve screening and cancer control. It aims to integrate multiple data sources to understand risk and etiology, with a focus on translating findings into better prevention and early detection strategies. The team plans to examine barriers to screening uptake and develop approaches to reduce overdiagnosis and unnecessary follow-up testing. The work involves collaboration across investigators to connect behavioral factors, biology, and screening outcomes to reduce mortality from lung cancer.
Why it matters
Potential benefit: If successful, the research could lead to better prevention strategies, improved screening guidelines, and fewer deaths from lung cancer through earlier and more accurate detection.
How similar studies have gone: Previous work has shown that integrated risk analyses can inform targeted prevention and screening, though this project adds broader translational elements.
Where this research is happening
-
University of New Mexico Health Scis Ctr
Albuquerque, United States Active
Researchers
- Principal investigator: Amos, Christopher I. — University of New Mexico Health Scis Ctr
- Study coordinator: Amos, Christopher I.
Related research
Other NIH-funded projects on the same topics.
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Blood-based markers to identify lung cancer risk in never-smokers
A researchers team at NYU School of Medicine is testing blood tests that might flag higher lung cancer risk in people who have never smoked, helping decide who might need screening.
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Integrative Analysis of Lung Cancer Risk and Causes
A large NIH project is exploring how tobacco use, behavior, biology, and screening practices influence lung cancer risk and outcomes to help prevent and detect it earlier.
-
Digital health strategies to expand lung cancer screening in safety-net clinics
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Proteomics-guided matching of lung cancer tumors to preclinical models
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Optimizing lung cancer care with smart tools for prevention, early detection, treatment, and survivorship
A U01 grant using AI and biomarkers to improve lung cancer prevention, screening, treatment, and survivorship care for people at risk or living with lung cancer.
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Integrated approach to lung screening and quitting for African Americans
A multi-level program aims to boost LDCT lung cancer screening uptake and help African American smokers quit, with support from a comprehensive community-focused plan.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.