Real-time urine oxygen monitor to prevent kidney injury during surgery
Official title: Real-Time, Non-Invasive Urine Oxygen Monitoring System for Acute Kidney Injury (AKI) Prevention
Funded at Kscube, LLC · NIH-11313673 · Data updated 2026-11-12
A new non-invasive urine oxygen monitor is being developed to identify risk of acute kidney injury in patients undergoing cardiac surgery or in the ICU so doctors can intervene early.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Kscube, LLC NIH-funded |
| Lab location | 1 site (Park City, United States) |
| Project start | August 21, 2026 |
| Project end | July 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $315,335 |
| NIH project number | 1R43DK143844-01A1 |
| Project ID | NIH-11313673 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults undergoing cardiac surgery or in intensive care units who are at risk for AKI and could benefit from early intervention.
✕Less likely to help
Patients not at risk for AKI or those not requiring perioperative monitoring may not benefit from this technology.
What this research studies
This project aims to create a wearable or non-invasive device that continuously measures oxygen levels in urine to detect kidney stress in real time. By providing immediate feedback during surgery and in the ICU, clinicians can apply preventive actions before kidney damage progresses. The approach builds on preliminary data suggesting intraoperative prediction of AKI, enabling timely interventions and potentially shorter hospital stays. The grant supports development, testing, and validation of the urine oxygen monitoring technology in a real-world clinical setting.
Why it matters
Potential benefit: If successful, patients could experience fewer AKI complications and better outcomes through earlier prevention and treatment.
How similar studies have gone: Early studies show promise in using urine-based monitoring to predict AKI, but this specific real-time oxygen monitoring approach is novel and progressing toward clinical use.
Where this research is happening
-
Kscube, LLC
Park City, United States Active
Researchers
- Principal investigator: Shumway, Spencer — Kscube, LLC
- Study coordinator: Shumway, Spencer
Related research
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Using smart computer predictions to prevent kidney injury after heart surgery
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.