REACH: A program to advance a cure for HIV
Official title: REACH: Research Enterprise to Advance a Cure for HIV
Funded at Weill Medical Coll of Cornell Univ · NIH-11515076 · Data updated 2026-11-12
A comprehensive program aimed at using the body’s immune cells and new biologics to achieve durable HIV remission or cure for people living with HIV.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Weill Medical Coll of Cornell Univ NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project start | August 16, 2021 |
| Project end | June 30, 2028 |
| Funding year | 2026 |
| Award (this year) | $5,414,805 |
| NIH project number | 4UM1AI164565-06 |
| Project ID | NIH-11515076 on NIH RePORTER |
Who could benefit from this research
✓Could help
People living with HIV who have achieved ART-controlled viremia and are interested in potential cure strategies.
✕Less likely to help
Individuals not eligible for the proposed immune-based approaches or who do not pursue cure-focused options may not experience direct benefit.
What this research studies
This grant supports a multi-year effort to understand how HIV persists in the body and how immune cells, like NK and T cells, can be harnessed with next-generation antiviral biologics to achieve lasting remission or eradication. Researchers will explore fundamental biology around the HIV reservoir, cellular immunity, and translational steps toward therapies that could reduce or eliminate the need for daily antiretroviral therapy. The work is designed to move from basic science toward practical treatment approaches that could benefit people living with HIV.
Why it matters
Potential benefit: If successful, the program could lead to durable remission or a true cure for HIV, reducing the lifetime burden of treatment for patients.
How similar studies have gone: Previous work has shown that immune-based strategies can contribute to HIV remission in rare cases, but a scalable cure approach remains a major research frontier.
Where this research is happening
-
Weill Medical Coll of Cornell Univ
New York, United States Active
Researchers
- Principal investigator: Jones, R. Brad — Weill Medical Coll of Cornell Univ
- Study coordinator: Jones, R. Brad
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.