PROSPERing: Tailored Exercise in HIV Care to Ease Symptoms and Support Healthy Aging
Official title: PROSPERing: Integrating Exercise into Routine HIV Care to Manage Symptoms and Promote Healthy Aging
Funded at University of Michigan at Ann Arbor · NIH-11404754 · Data updated 2026-11-12
A clinic-based, personalized exercise program for adults living with HIV is being tested to help reduce symptom burden and promote healthier aging.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 16, 2026 |
| Project end | June 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $815,826 |
| NIH project number | 1R01NR022022-01A1 |
| Project ID | NIH-11404754 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with HIV who can participate in a clinic-based exercise program and follow-up contacts.
✕Less likely to help
Patients unable to participate in physical activity or follow-up calls may receive no direct benefit.
What this research studies
This project builds on a previous study to clearly map how fitness, activity, and symptom burden relate in adults with HIV. Participants will have their cardiorespiratory fitness measured with VO2 max and will wear accelerometers to track activity, with symptom data collected regularly. They will be randomized to receive a tailored, clinic-based exercise program plus follow-up calls for a year versus standard exercise counseling, across four diverse sites. The goal is to see if a scalable, gym-based plan can reduce symptoms and improve overall well-being in people living with HIV.
Why it matters
Potential benefit: If successful, patients with HIV could experience fewer symptoms and better quality of life through a practical, clinic-based exercise program.
How similar studies have gone: Prior PROSPER-HIV work showed meaningful symptom reductions and useful relationships between activity and symptoms, with several related publications and ongoing analyses.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Webel, Allison R — University of Michigan at Ann Arbor
- Study coordinator: Webel, Allison R
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.