Costa Rica long-lived older adults follow-up (Wave 4)

Costa Rican Longevity and Healthy Aging Study (CRELES): Wave 4

['FUNDING_R01'] · UNIVERSITY OF CALIFORNIA BERKELEY · NIH-11468150

We will re-contact Costa Rican adults aged 70 and older (and their spouses) to collect health, thinking, and blood information to find what helps people live longer and stay mentally sharp.

Quick facts

Phase['FUNDING_R01']
Study typeNih_funding
SexAll
SponsorUNIVERSITY OF CALIFORNIA BERKELEY (nih funded)
Locations1 site (BERKELEY, UNITED STATES)
Trial IDNIH-11468150 on ClinicalTrials.gov

What this research studies

If you joined CRELES before, researchers will try to re-interview you and your spouse in this fourth wave to continue a long-term look at aging in Costa Rica. The visit includes a detailed interview, physical health measurements, a blood draw for biomarkers, cognitive performance tests, and informant interviews using the Harmonized Cognitive Assessment Protocol (HCAP). The team expects to attempt interviews with over 3,500 surviving panel members and will link information to vital records for long-term outcomes. Findings aim to show which health, social, and biological factors relate to longevity and lower dementia risk in this population.

Who could benefit from this research

Good fit: Ideal participants are Costa Rican adults aged 70+ who took part in earlier CRELES waves, plus their current spouses regardless of age.

Not a fit: People who do not live in Costa Rica or who were not part of the CRELES panel are unlikely to be enrolled or directly benefit from this wave.

Why it matters

Potential benefit: Results could point to real-world factors that protect against dementia and support healthier, longer lives in older adults.

How similar studies have performed: Other long-running population cohorts and the HCAP approach have successfully identified dementia risk and protective factors, so this approach builds on proven methods.

Where this research is happening

BERKELEY, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Alzheimer's Disease and its related dementias

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.