NIH-funded research NIH-funded research

Primary care loneliness programs to prevent suicide

Official title: Development and Pilot Study of Primary Care Loneliness Interventions to Prevent Suicide

Funded at University of Michigan at Ann Arbor · NIH-11084462 · Data updated 2026-11-12

This project will try two short loneliness programs—social prescribing and brief cognitive therapy—in primary care to help adults who feel lonely and may have suicidal thoughts.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startJuly 15, 2023
Project endSeptember 30, 2026
Funding year2025
Award (this year)$234,000
NIH project number5R34MH132808-03
Project IDNIH-11084462 on NIH RePORTER

Who could benefit from this research

Could help

Adults (age 21+) seen in participating primary care clinics who report significant loneliness and may have depression, anxiety, or suicidal thoughts would be ideal candidates.

Less likely to help

People who are not lonely, who need intensive specialty psychiatric care (for example active suicidal intent, psychosis, or severe substance use), or who cannot access participating clinics may not benefit from these brief primary care interventions.

What this research studies

If you're an adult visiting a primary care clinic and feel lonely, this project adapts two brief approaches—social prescribing, which links you to community activities, and brief cognitive therapy, which teaches skills to change unhelpful thoughts—for delivery by behavioral health staff in primary care. In a pilot three-arm randomized design, patients will be assigned to social prescribing, brief cognitive therapy, or usual care to see which approach most reduces loneliness and suicidal ideation. The team will work with primary care behavioral health care managers to tailor the programs to clinic workflows and will measure loneliness, mood, and safety-related outcomes over the study period. The project focuses on adults aged 21 and older.

Why it matters

Potential benefit: If successful, these approaches could give primary care teams practical tools to reduce loneliness and lower suicide risk for patients.

How similar studies have gone: Previous primary care loneliness programs have had mixed results, though social prescribing and brief cognitive therapies have shown promise in other settings but are not yet established in primary care.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Pfeiffer, Paul Nelson — University of Michigan at Ann Arbor
  • Study coordinator: Pfeiffer, Paul Nelson

Related research

Other NIH-funded projects on the same topics.

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  • Using AI on health record notes to find loneliness and suicide risk in older adults

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  • Preventing teen suicide through confidential care in primary care clinics

    This study is looking at how well private care can help prevent suicide in teens by making it easier for them to talk about their feelings and get the support they need during doctor visits.

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  • Improving Suicide Prevention in Primary Care

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  • Improving suicide prevention methods for children in primary care settings

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    NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11063233

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.