NIH-funded research NIH-funded research

Preventing Mood and Anxiety Problems After Cesarean Delivery

Official title: Preventing Maternal Mood, Anxiety, and Trauma Symptoms after Cesarean Delivery

Funded at University of Colorado Denver · NIH-11394478 · Data updated 2026-11-12

A low-cost, one-hour intervention given to pregnant patients having a cesarean delivery to help reduce mood, anxiety, and trauma symptoms later on.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Colorado Denver
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startMay 3, 2024
Project endApril 30, 2027
Funding year2026
Award (this year)$189,000
NIH project number5R34MH133685-03
Project IDNIH-11394478 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant individuals at high risk for PMATS who are planning a cesarean delivery and are open to a one-session preventive intervention.

Less likely to help

Individuals not undergoing cesarean delivery or those who do not experience PMATS risk factors may derive little or no benefit.

What this research studies

This project plans to offer a brief, single-session cognitive-behavioral approach designed for high-risk pregnancies requiring cesarean delivery. It builds on prior work showing that a one-hour program can lessen anxiety sensitivity and traumatic stress around surgery. The intervention includes psychoeducation and a controlled exposure to the operating room experience, aiming to prevent PMATS before they start. The study will be conducted with pregnant patients at risk for PMATS, with the goal of making mental health support more accessible and affordable.

Why it matters

Potential benefit: If successful, the program could reduce the risk of mood and anxiety disorders after cesarean delivery for mothers and improve overall perinatal well-being.

How similar studies have gone: Previous small studies suggest single-session interventions can reduce anxiety-related symptoms around surgical events, but larger trials are needed for conclusive evidence.

Where this research is happening

  • University of Colorado Denver
    Aurora, United States
    Active

Researchers

  • Principal investigator: Wood, Cristina L — University of Colorado Denver
  • Study coordinator: Wood, Cristina L

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.