NIH-funded research NIH-funded research

Stepped care for pregnancy-related mood and anxiety for women with HIV in Kenya

Official title: Integration of stepped care for Perinatal Mood and Anxiety Disorders among Women Living with HIV in Kenya

Funded at Kenyatta National Hospital · NIH-11144411 · Data updated 2026-11-12

This project brings routine mental-health screening, brief counseling, and remote psychiatric care together to help pregnant and postpartum women living with HIV in Kenyan clinics who have depression or anxiety.

More Anxiety research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionKenyatta National Hospital
NIH-funded
Lab location1 site (Nairobi, Kenya)
Project startSeptember 19, 2023
Project endJuly 31, 2028
Funding year2025
Award (this year)$1,807,527
NIH project number4RF1MH133266-03
Project IDNIH-11144411 on NIH RePORTER

Who could benefit from this research

Could help

Pregnant or postpartum women living with HIV who attend participating antenatal, postnatal, or PMTCT clinics in Kenya and screen positive for depression or anxiety are the intended candidates.

Less likely to help

Women who do not attend participating clinics, who do not screen positive, or who need urgent inpatient or highly specialized psychiatric care may not receive direct benefit from this program.

What this research studies

If you go to a participating maternal or PMTCT clinic, staff will screen you for depression and anxiety as part of routine visits. If you have mild-to-moderate symptoms, you could be offered Problem Management Plus (PM+), a short counseling program delivered by trained clinic providers. If your symptoms are severe or do not improve, the program can connect you with a psychiatrist by telemedicine. The team will train clinic staff and set up referral links so this package can work as part of regular HIV and maternity care.

Why it matters

Potential benefit: If successful, this could make mental health care easier to get where you already receive HIV and maternity services, reducing depression and anxiety and supporting better outcomes for you and your baby.

How similar studies have gone: Components like PM+ and stepped-care models have reduced perinatal depression in low-resource settings, though combining them with telepsychiatry specifically for women living with HIV is more novel.

Where this research is happening

  • Kenyatta National Hospital
    Nairobi, Kenya
    Active

Researchers

  • Principal investigator: Kinuthia, John — Kenyatta National Hospital
  • Study coordinator: Kinuthia, John

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.