PrEP use for Black cisgender women: making HIV prevention more accessible
Official title: RFA-PS-23-001 - Project PrOVIDE: PrEP Optimization Via Implementation, Dissemination, and Evaluation
Funded at Lurie Children's Hospital of Chicago · NIH-11500991 · Data updated 2026-11-12
This project tests practical strategies to help Black cisgender women in six U.S. counties start and keep using HIV PrEP.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Lurie Children's Hospital of Chicago NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 30, 2023 |
| Project end | September 29, 2027 |
| Funding year | 2026 |
| Award (this year) | $1,862,377 |
| NIH project number | 5U01PS005270-04 |
| Project ID | NIH-11500991 on NIH RePORTER |
Who could benefit from this research
✓Could help
Black cisgender women in care across six counties who could benefit from PrEP.
✕Less likely to help
Individuals outside the PrEP care continuum or who choose not to use PrEP may see little or no benefit.
What this research studies
This grant supports implementing proven PrEP improvement methods in real health care settings to reach Black cisgender women at risk for HIV. It uses education for patients, provider training, electronic health record tools, navigation support, clinical champions, and mobile health tools to boost PrEP initiation and persistence. The team will adapt these strategies, implement them in clinics, and study how well they work in improving PrEP care along the care continuum. Results will guide future efforts to tailor PrEP programs to communities most in need.
Why it matters
Potential benefit: If successful, patients at risk could access PrEP more easily and stay on it longer, reducing new HIV infections.
How similar studies have gone: Prior work has shown some success with similar implementation strategies among other populations, but evidence for Black cisgender women is limited and this study aims to expand that.
Where this research is happening
-
Lurie Children's Hospital of Chicago
Chicago, United States Active
Researchers
- Principal investigator: Johnson, Amy Kristen — Lurie Children's Hospital of Chicago
- Study coordinator: Johnson, Amy Kristen
Related research
Other NIH-funded projects on the same topics.
-
mChoice: Boosting PrEP Use and Adherence for Black and Latino MSM with Tailored Training and Support
A national study to help Black and Latino men who have sex with men start and stick with PrEP through culturally matched provider training and patient support.
-
Harnessing male peer networks to boost HIV testing and PrEP use
A large clinical trial in South Africa tests whether giving HIV self-test kits through male peer networks, with phone support, increases PrEP uptake among men.
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Harnessing men's peer networks to boost HIV self-testing and PrEP use
A large project in South Africa tests whether giving HIV self-test kits through men’s social networks, with phone support, can lead to more men starting PrEP and using HIV testing.
-
Participatory system dynamics to improve PrEP access in the Bronx
A community-driven project in the Bronx will use system dynamics to identify practical ways to help people at risk for HIV start and stay on PrEP.
-
TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
-
CARES: A practical program to help adolescent girls and young women use PrEP in Africa
A program called CARES helps young women in South Africa and Zimbabwe use different PrEP options better, with counseling, reminders, and options for support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.