TB PrEP: Bringing HIV prevention to households affected by TB in Uganda
Official title: TB PrEP - Integrating HIV prevention with TB household contact evaluation
Funded at University of Washington · NIH-11590744 · Data updated 2026-11-12
Aims to help people in households with TB in Uganda access HIV PrEP as part of a combined prevention approach.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Washington NIH-funded |
| Lab location | 1 site (Seattle, United States) |
| Project start | September 9, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $232,311 |
| NIH project number | 3R01MH134685-03S1 |
| Project ID | NIH-11590744 on NIH RePORTER |
Who could benefit from this research
✓Could help
HIV-negative individuals, especially adults and adolescents in households affected by TB in Uganda, who have substantial exposure to HIV.
✕Less likely to help
Individuals with HIV infection, or those unwilling to use PrEP, may not benefit from this approach.
What this research studies
This project tests a care model that links HIV testing and PrEP to TB household contact investigation in high-burden settings. It focuses on adults and adolescents in Uganda to see if integrating PrEP into TB outreach increases HIV prevention uptake and reduces new infections. The study builds on prior evidence that household-based approaches can improve access to PrEP and improve care for people exposed to both TB and HIV. Results will guide scalable strategies to combine TB and HIV prevention in community settings.
Why it matters
Potential benefit: If successful, it could increase PrEP use among people at high risk, reducing new HIV infections in TB-affected households.
How similar studies have gone: Previous studies show household-based PrEP linkage is feasible and beneficial in high HIV-burden settings, supporting this approach as promising.
Where this research is happening
-
University of Washington
Seattle, United States Active
Researchers
- Principal investigator: Ross, Jennifer M — University of Washington
- Study coordinator: Ross, Jennifer M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.