Precision Cardiovascular Diseases in the South Asian CARRS Cohort
Official title: Precision Cardiovascular Diseases Phenotyping and Pathophysiological Pathways in the CARRS Cohort (Precision-CARRS)
Funded at Emory University · NIH-11617879 · Data updated 2026-11-12
This grant aims to improve how heart disease risk is predicted and managed for South Asian adults by adding detailed health measurements and real-time behavior data to a large ongoing cohort.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Emory University NIH-funded |
| Lab location | 1 site (Atlanta, United States) |
| Project start | May 15, 2022 |
| Project end | February 28, 2027 |
| Funding year | 2026 |
| Award (this year) | $163,834 |
| NIH project number | 3P01HL154996-05S4 |
| Project ID | NIH-11617879 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults of South Asian descent (age 20+), with ongoing follow-up in the CARRS cohort or similar populations, who consent to extended phenotyping and biospecimen analyses.
✕Less likely to help
Individuals outside the South Asian population or those not eligible for long-term follow-up may not directly benefit.
What this research studies
Precision-CARRS will enhance early prediction and personalized care for atherosclerotic cardiovascular disease and heart failure by integrating genetic, environmental, behavioral, and biological factors. The project builds on the NHLBI-supported CARRS cohort of over 21,000 South Asians aged 20 and older, with extensive follow-up and a large biorepository. Researchers will add deep phenotyping, targeted protein markers, untargeted omics, and real-time behavior monitoring to better understand why ASCVD develops and progresses in this population. By extending follow-up for five more years, the study expects thousands of person-years of data and hundreds of new ASCVD events to refine risk predictions and intervention strategies. The work is designed to translate complex data into actionable insights to improve prevention and care for South Asians at risk of cardiovascular disease.
Why it matters
Potential benefit: Improved, more personalized prevention and treatment strategies for ASCVD and heart failure in South Asian adults.
How similar studies have gone: Building on the established CARRS cohort, this project aims to extend and deepen proven methods with added omics and phenotyping to achieve more precise risk stratification.
Where this research is happening
-
Emory University
Atlanta, United States Active
Researchers
- Principal investigator: Narayan, Kabayam M Venkat — Emory University
- Study coordinator: Narayan, Kabayam M Venkat
Related research
Other NIH-funded projects on the same topics.
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Precision cardiovascular disease profiling in South Asians (CARRS)
A large study from Emory will create a detailed, personalized portrait of heart disease risk and early disease markers in South Asian adults to improve future prevention.
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Precision cardiovascular profiling in South Asians to improve ASCVD prediction
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.