NIH-funded research R03 grant

Positive emotions may help older adults with memory problems handle stress better

Official title: The role of positive emotions in stress-induced negative emotion regulation among older adults with mild cognitive impairment

Funded at University of Rochester · NIH-11353762 · Data updated 2026-11-12

A small NIH grant will explore whether nurturing positive feelings can help older adults with mild cognitive impairment cope with stress and reduce negative mood.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionUniversity of Rochester
NIH-funded
Lab location1 site (Rochester, United States)
Project startSeptember 15, 2026
Project endAugust 31, 2028
Funding year2026
Award (this year)$302,084
NIH project number1R03AG101174-01
Project IDNIH-11353762 on NIH RePORTER

Who could benefit from this research

Could help

Older adults (typically 60+) with mild cognitive impairment or early Alzheimer’s-related conditions who experience stress-related mood changes.

Less likely to help

People without MCI, without interest in stress-related mood management, or those unable to participate due to cognitive or physical limitations.

What this research studies

This project looks at how positive emotions influence how older adults with MCI manage stress and regulate negative emotions. It will involve a short, structured approach to observe mood responses under stress and test whether strategies to boost positive feelings can lessen negative mood. The study uses human participants aged 21+ with AD-related conditions and will collect mood and stress data to understand potential benefits. Results could point to simple, person-centered ways to improve daily well-being for people at risk of dementia progression.

Why it matters

Potential benefit: If successful, the work could inform non-drug approaches to lessen stress-related mood problems in older adults with MCI.

How similar studies have gone: Preliminary work suggests positive emotions may buffer stress in dementia caregivers; evidence in MCI is still emerging.

Where this research is happening

  • University of Rochester
    Rochester, United States
    Active

Researchers

  • Principal investigator: Lin, Sin Yi Rose — University of Rochester
  • Study coordinator: Lin, Sin Yi Rose

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.