Personalized sleep help: real-time, at-home strategies to improve sleep and breathing problems
Official title: Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders
Funded at Northwestern University · NIH-11397518 · Data updated 2026-11-12
A study at Northwestern University will test new real-time sleep-modulation methods at home to help people with sleep apnea and related conditions feel better and sleep more soundly.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Northwestern University NIH-funded |
| Lab location | 1 site (Chicago, United States) |
| Project start | September 10, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $3,360,000 |
| NIH project number | 7DP1HL179370-03 |
| Project ID | NIH-11397518 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with sleep-disordered breathing or related sleep problems who can use home monitoring systems and participate in at-home sleep sessions.
✕Less likely to help
Individuals whose sleep issues are caused by non-sleep-related medical conditions or cannot tolerate at-home monitoring may not benefit.
What this research studies
This project aims to use real-time monitoring and gentle in-home interventions to influence how people sleep, with the goal of reducing breathing disruptions and improving overall health. Researchers will combine advanced sleep monitoring (nasal airflow, in-ear EEG, chest heart signals) with soft-sound cues to gently guide sleep physiology. The approach is built on ideas that sleep-related memories and habits can be nudged to produce healthier sleep patterns. Participants would use home equipment to allow natural sleep in their own environment. The study blends neuroscience insights with practical, noninvasive strategies to promote better rest.
Why it matters
Potential benefit: If successful, this approach could lead to better sleep quality and fewer breathing interruptions for people with sleep apnea and related conditions.
How similar studies have gone: Past work showed that sleep-related brain activity can be influenced noninvasively, but applying it to real-time home-based health benefits is promising but still experimental.
Where this research is happening
-
Northwestern University
Chicago, United States Active
Researchers
- Principal investigator: Paller, Ken a — Northwestern University
- Study coordinator: Paller, Ken a
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.