NIH-funded research NIH-funded research

Personalized sleep help: real-time, at-home strategies to improve sleep and breathing problems

Official title: Micromanaging Human Sleep Physiology to Treat Sleep Apnea and Other Disorders

Funded at Northwestern University · NIH-11397518 · Data updated 2026-11-12

A study at Northwestern University will test new real-time sleep-modulation methods at home to help people with sleep apnea and related conditions feel better and sleep more soundly.

More Sleep Apnea research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNorthwestern University
NIH-funded
Lab location1 site (Chicago, United States)
Project startSeptember 10, 2024
Project endAugust 31, 2029
Funding year2026
Award (this year)$3,360,000
NIH project number7DP1HL179370-03
Project IDNIH-11397518 on NIH RePORTER

Who could benefit from this research

Could help

Adults with sleep-disordered breathing or related sleep problems who can use home monitoring systems and participate in at-home sleep sessions.

Less likely to help

Individuals whose sleep issues are caused by non-sleep-related medical conditions or cannot tolerate at-home monitoring may not benefit.

What this research studies

This project aims to use real-time monitoring and gentle in-home interventions to influence how people sleep, with the goal of reducing breathing disruptions and improving overall health. Researchers will combine advanced sleep monitoring (nasal airflow, in-ear EEG, chest heart signals) with soft-sound cues to gently guide sleep physiology. The approach is built on ideas that sleep-related memories and habits can be nudged to produce healthier sleep patterns. Participants would use home equipment to allow natural sleep in their own environment. The study blends neuroscience insights with practical, noninvasive strategies to promote better rest.

Why it matters

Potential benefit: If successful, this approach could lead to better sleep quality and fewer breathing interruptions for people with sleep apnea and related conditions.

How similar studies have gone: Past work showed that sleep-related brain activity can be influenced noninvasively, but applying it to real-time home-based health benefits is promising but still experimental.

Where this research is happening

  • Northwestern University
    Chicago, United States
    Active

Researchers

  • Principal investigator: Paller, Ken a — Northwestern University
  • Study coordinator: Paller, Ken a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.