Patient-Caregiver Dyadic Program to Reduce Distress for Older Adults with Cancer and Mild Cognitive Impairment
Official title: A Patient-Caregiver Behavioral Intervention for Older Adults with Cancer and Mild Cognitive Impairment
Funded at Duke University · NIH-11398081 · Data updated 2026-11-12
A five-year program to help older cancer patients with mild cognitive impairment and their family caregivers cope with distress and improve communication.
Quick facts
| Grant type | Career grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Duke University NIH-funded |
| Lab location | 1 site (Durham, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $162,097 |
| NIH project number | 5K08CA258947-05 |
| Project ID | NIH-11398081 on NIH RePORTER |
Who could benefit from this research
✓Could help
Older adults (65+) with cancer and pre-existing mild cognitive impairment and their family caregivers who are involved in care decisions.
✕Less likely to help
Patients without distress or without a participating caregiver may see limited benefit.
What this research studies
This NIH K08 career development effort at Duke University will create and pilot a dyadic behavioral intervention (COPE+) designed for older adults with cancer and pre-existing mildly cognitive impairment and their informal caregivers. The project aims to reduce depression and anxiety while enhancing communication about care priorities, symptoms, and decisions within the patient-caregiver dyad. The research combines development, training, and small-scale testing to establish feasibility and guide future translational work in oncology and palliative care settings. Outcomes will focus on distress levels, patient-caregiver communication, and quality of life from the perspective of both members of the dyad.
Why it matters
Potential benefit: If successful, patients and their caregivers could experience reduced distress and better aligned care planning and communication.
How similar studies have gone: Prior individually based oncology and palliative care interventions have shown promise; this program extends the approach to a dyadic format specific to cancer with MCI.
Where this research is happening
-
Duke University
Durham, United States Active
Researchers
- Principal investigator: Ramos, Katherine — Duke University
- Study coordinator: Ramos, Katherine
Related research
Other NIH-funded projects on the same topics.
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Improving communication and reducing distress for older cancer patients with mild cognitive impairment and their caregivers
This study is testing a friendly program called COPE+ to help older adults with cancer and mild memory issues feel better emotionally and communicate more easily with their family caregivers, making life a little easier for everyone involved.
-
Improving Neurological Health with Brain Training for Mild Cognitive Impairment (INHANCE-MCI)
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This project uses brain imaging to study how the cholinergic system and Alzheimer’s pathology unfold in people at risk for dementia.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.