Parent-child trio study of pediatric anxiety disorders
Funded at Yale University · NIH-11427134 · Data updated 2026-11-12
A family-based genetic study aims to identify DNA factors that contribute to anxiety disorders in children.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Yale University NIH-funded |
| Lab location | 1 site (New Haven, United States) |
| Project start | September 10, 2026 |
| Project end | August 31, 2031 |
| Funding year | 2026 |
| Award (this year) | $830,833 |
| NIH project number | 1R01MH145308-01 |
| Project ID | NIH-11427134 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children with anxiety disorders (and their families) who are in the age range studied and may participate through sequencing and data sharing.
✕Less likely to help
Children without anxiety disorders or without access to DNA sequencing and family data collection may not directly benefit.
What this research studies
This project will study DNA from children with anxiety disorders and their parents to find genetic factors that raise risk. By sequencing many family trios, researchers hope to uncover rare and inherited genetic variants that influence anxiety in kids and how environment might interact with these factors. The study builds on previous work with family data and plans to analyze variants and affected pathways to understand biology and potential clinical implications. Results could illuminate new targets for prevention and treatment in pediatric anxiety and related conditions.
Why it matters
Potential benefit: If successful, the research could lead to better understanding of the genetic basis of pediatric anxiety and inform more personalized approaches to prevention and care.
How similar studies have gone: Prior pediatric genetics studies have identified risk genes in other disorders, with growing potential to reveal targets for anxiety as well.
Where this research is happening
-
Yale University
New Haven, United States Active
Researchers
- Principal investigator: Olfson, Emily Hunt — Yale University
- Study coordinator: Olfson, Emily Hunt
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.