NIH-funded research NIH-funded research

Optimizing knee replacement rehab with a personalized, veteran-focused plan

Official title: Optimizing Rehabilitation Prescription after Knee Replacement: Advancing the "people-like-me" approach for Veteran-centered Care

Funded at VA Eastern Colorado Health Care System · NIH-11348061 · Data updated 2026-11-12

A study to help Veterans recover better after knee replacement by comparing a new, personalized rehab plan to typical care using real patient histories.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Eastern Colorado Health Care System
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startJuly 1, 2026
Project endJune 30, 2031
Funding year2026
NIH project number1IK2RD000357-01A1
Project IDNIH-11348061 on NIH RePORTER

Who could benefit from this research

Could help

Veterans who have had or are about to have a total knee replacement and receive care through the VA

Less likely to help

Patients whose recovery does not follow typical patterns or who have contraindications to enhanced rehab may see no benefit.

What this research studies

This project uses a predictive, patient-centered approach to improve rehabilitation after total knee replacement for Veterans. It compares how a new “people-like-me” rehabilitation model performs against standard post-surgical care by looking at multiple recovery areas, not just one. By using pre- and post-operative data and historical patient stories, the team aims to tailor rehab plans to each individual’s recovery speed and needs. The goal is to identify which patients are at risk for poorer outcomes and adjust therapy accordingly.

Why it matters

Potential benefit: If successful, this approach could help more Veterans regain function and reduce persistent pain after knee replacement.

How similar studies have gone: Previous rehab studies struggled to predict outcomes; this project tests a more personalized, history-informed approach with potential for better prediction.

Where this research is happening

  • VA Eastern Colorado Health Care System
    Aurora, United States
    Active

Researchers

  • Principal investigator: Graber, Jeremy — VA Eastern Colorado Health Care System
  • Study coordinator: Graber, Jeremy

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.