NIH-funded research NIH-funded research

Exercise and brain biology of stress-related eating in Veterans

Official title: Exercise Effects on the Neurobiology Underlying Stress-Related Eating Behaviors in Veterans

Funded at VA Eastern Colorado Health Care System · NIH-11413118 · Data updated 2026-11-12

This project explores how endurance exercise could change the brain processes that drive stress-related eating in Veterans.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionVA Eastern Colorado Health Care System
NIH-funded
Lab location1 site (Aurora, UNITED STATES)
Project startSeptember 1, 2025
Project endAugust 31, 2030
Funding year2027
NIH project number5I01CX002752-02
Project IDNIH-11413118 on NIH RePORTER

Who could benefit from this research

Could help

Veterans who experience overweight or obesity with stress-related eating behaviors.

Less likely to help

Individuals without stress-related eating patterns or obesity may see limited benefit.

What this research studies

The study looks at how stress affects eating and how exercise might change the brain networks involved in reward and self-control that influence food choices. It focuses on Veterans and aims to see if a structured endurance exercise program can alter neurobiological mechanisms linked to stress-related eating. Researchers will examine brain function and eating behaviors to identify potential pathways where exercise helps reduce cravings and unhealthy food choices under stress.

Why it matters

Potential benefit: If successful, the work could lead to exercise-based strategies to reduce stress-driven overeating and improve health in Veterans.

How similar studies have gone: Previous work suggests exercise can improve stress responses, but direct links to neurobiology of stress-related eating are still being explored.

Where this research is happening

  • VA Eastern Colorado Health Care System
    Aurora, United States
    Active

Researchers

  • Principal investigator: Legget, Kristina T — VA Eastern Colorado Health Care System
  • Study coordinator: Legget, Kristina T

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.