NIH-funded research NIH-funded research

Optimizing HIV prevention for high-risk meth-using men who have sex with men

Official title: Optimizing HIV prevention for high-risk methamphetamine-using men who have sex with men

Funded at Graduate School of Public Health and Health Policy · NIH-11362220 · Data updated 2026-11-12

A large HIV prevention project focuses on meth-using MSM to understand why HIV risk is higher and to test telehealth coaching to help them start or stay on PrEP.

More HIV Prevention research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionGraduate School of Public Health and Health Policy
NIH-funded
Lab location1 site (New York, United States)
Project startApril 8, 2022
Project endApril 30, 2027
Funding year2026
Award (this year)$2,249,856
NIH project number5UH3AI169652-05
Project IDNIH-11362220 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are men who have sex with men, use meth, and are at risk for HIV or considering PrEP.

Less likely to help

People not at risk for HIV or not interested in PrEP may see limited direct benefit.

What this research studies

This project follows an urgent HIV prevention need among men who have sex with men who use meth. It combines looks at social, structural, and biological factors to understand seroconversion risk and tests a telehealth motivational program to help MSM enter or re-enter the PrEP care pathway. A new prospective cohort of 5,000 MSM will be enrolled, including 3,000 meth users and 2,000 non-users, with comprehensive biospecimen and behavioral data. The study aims to map where meth use and HIV risk intersect, how to support PrEP access, and whether meth use influences rectal immune factors related to HIV risk. Results could guide targeted interventions to reduce new HIV infections in this high-risk group.

Why it matters

Potential benefit: If successful, the program could improve PrEP access and reduce HIV infections among meth-using MSM.

How similar studies have gone: Prior studies show meth use increases HIV risk among MSM, and telehealth PrEP support has shown promise in improving access in some settings.

Where this research is happening

  • Graduate School of Public Health and Health Policy
    New York, United States
    Active

Researchers

  • Principal investigator: Grov, Christian — Graduate School of Public Health and Health Policy
  • Study coordinator: Grov, Christian

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.