NIH-funded research R01 grant

Optimization of a sexual and reproductive health program for Latina teens and their female caregivers

Official title: Optimization trial of a sexual and reproductive health program for Latina teens and their female caregivers

Funded at University of Illinois at Chicago · NIH-11405336 · Data updated 2026-11-12

A program called Floreciendo helps Latina teens (14–18) and their female caregivers in Chicago-based communities improve sexual and reproductive health through culturally matched guidance.

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Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Illinois at Chicago
NIH-funded
Lab location1 site (Chicago, UNITED STATES)
Project startSeptember 11, 2026
Project endJune 30, 2031
Funding year2026
Award (this year)$801,644
NIH project number1R01HD122528-01
Project IDNIH-11405336 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants are Latina teens aged 14-18 and their female caregivers, willing to participate with support from community organizations in the Chicago area.

Less likely to help

Teens or caregivers not engaged with community organizations or not residing in the Chicago metro area may not benefit.

What this research studies

This grant tests how to best structure a health program for Latina teens and their caregivers to reduce risky sexual behaviors and improve health outcomes. It uses a randomized optimization approach to find the most effective mix of program components, delivered by Latina staff in community organizations. About 300 teen-caregiver pairs will participate in an 8–12 month study across Chicago, with all participants receiving a foundational session on sexual decision-making. The study is guided by the MOST framework to identify practical, scalable components for real-world use. Outcomes will include sexual health knowledge, decision-making, and related health behaviors.

Why it matters

Potential benefit: If successful, the program could reduce STI/HIV risk and unplanned pregnancies among Latina teens by enhancing family- and community-centered support.

How similar studies have gone: Previous pilot work showed feasibility and acceptability, with early signals of positive health effects.

Where this research is happening

  • University of Illinois at Chicago
    Chicago, United States
    Active

Researchers

  • Principal investigator: Merrill, Katherine Gannett — University of Illinois at Chicago
  • Study coordinator: Merrill, Katherine Gannett

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.