Non-invasive spinal stimulation to boost how the spine's sensorimotor network adapts after spinal cord injury

Who could benefit from this research

What this research studies

This project compares transcutaneous spinal stimulation (TSS) and epidural spinal stimulation (ESS) in the same participants to see how each technique interacts with rehabilitation training. It looks at immediate and longer-term motor and neurophysiological responses during standing tasks, aiming to understand why stimulation helps motor function.  The researchers will map neurophysiological profiles and measure functional outcomes to determine which approach, or combination, best supports recovery. The study will involve participants with spinal cord injury undergoing rehabilitation while receiving either TSS or ESS to maximize motor gains. Results could guide personalized approaches to improve standing and mobility after SCI.

Why it matters

Where this research is happening

• Methodist Hospital Research Institute
  Houston, United States Active

Researchers

• Principal investigator: Sayenko, Dimitry — Methodist Hospital Research Institute
• Study coordinator: Sayenko, Dimitry

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About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.