Mouse Phenotyping Data Resource to Link Genes with Disease,”
Official title: Mouse Phenotyping Informatics Infrastructure - Data acquisition, integration, analysis and translation of high throughput mammalian phenotyping data.
Funded at European Molecular Biology Laboratory · NIH-11580389 · Data updated 2026-11-12
A large international project uses mouse biology to connect genes to diseases and provide ready-to-use mouse strains for researchers and clinicians.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | European Molecular Biology Laboratory NIH-funded |
| Lab location | 1 site (Heidelberg, Germany) |
| Project start | September 16, 2011 |
| Project end | June 30, 2027 |
| Funding year | 2026 |
| Award (this year) | $301,622 |
| NIH project number | 3UM1HG006370-15S1 |
| Project ID | NIH-11580389 on NIH RePORTER |
Who could benefit from this research
✓Could help
Not applicable (preclinical research resource; not a patient-intervention study).
✕Less likely to help
Direct patient benefits are unlikely in the short term; this is a tool for researchers.
What this research studies
The MPI2 project creates and curates a vast, standardized dataset of mouse phenotypes to help scientists understand how genes relate to human diseases. It focuses on acquiring, analyzing, and integrating high-throughput imaging and phenotyping data, and makes this information available with quality control and FAIR data practices. Researchers and patients may benefit from improved models of cardiac and other diseases, with potential downstream insights for diagnosis and treatment. The work involves collaborations across laboratories and uses advanced analytics to map mouse findings to human disease knowledge. Access to well-characterized mouse strains and data could accelerate translational research and new therapeutic ideas.
Why it matters
Potential benefit: Could speed up discovery of gene-disease links and lead to better disease models and therapies.
How similar studies have gone: Past mouse phenotyping efforts have produced valuable disease models and insights linking genes to human conditions.
Where this research is happening
-
European Molecular Biology Laboratory
Heidelberg, Germany Active
Researchers
- Principal investigator: Parkinson, Helen Elizabeth — European Molecular Biology Laboratory
- Study coordinator: Parkinson, Helen Elizabeth
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.