NIH-funded research NIH-funded research

Motivational interview approach to boost use of drug checking and safer drug use to prevent overdoses

Official title: Efficacy and implementation considerations for a peer-led motivational interviewing intervention to promote uptake of drug checking services and safer drug use behaviors to reduce overdose

Funded at University of California, San Diego · NIH-11333034 · Data updated 2026-11-12

A community-based program led by peers uses a brief motivational interview to help people who use drugs use drug-checking services more and adopt safer behaviors to reduce overdoses in San Diego.

More Drug Use research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 15, 2024
Project endMay 31, 2029
Funding year2026
Award (this year)$1,066,337
NIH project number5R33DA061260-03
Project IDNIH-11333034 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults 21+ who use drugs and participate in syringe service programs in San Diego County, with interest in drug checking and safer-use strategies.

Less likely to help

Individuals not using or not seeking harm-reduction services may derive limited benefit.

What this research studies

This project tests a peer-led, bilingual MI intervention called MI-CHANCE to encourage uptake of drug-checking services that use test strips and FTIR technology. It is a hybrid type 1 study aiming to measure overdose outcomes over 30 months and to explore how social and cognitive factors mediate effects. Participants are people who use drugs in San Diego County, with conversations designed to fit real-world SSP settings and reflect cultural needs, including Latinx communities. The study builds on existing harm-reduction services to see if a theory-based approach improves post-checking safer behaviors.

Why it matters

Potential benefit: If successful, the intervention could increase DCS use and lead to safer drug practices, potentially lowering overdose risk.

How similar studies have gone: Previous work suggests peer-led, theory-based counseling can influence health behaviors, but this specific approach to DCS uptake is relatively new.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Strathdee, Steffanie a — University of California, San Diego
  • Study coordinator: Strathdee, Steffanie a

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.