NIH-funded research NIH-funded research

MorpHiC Data Resource and Coordinating Center

Official title: MorPhiC Data Resource and Administrative Coordinating Center

Funded at University of Miami School of Medicine · NIH-11599438 · Data updated 2026-11-12

A national effort to build and share a comprehensive, high-quality catalogue of how human genes affect cell function when they’re turned off, using human cellular models.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Miami School of Medicine
NIH-funded
Lab location1 site (Coral Gables, United States)
Project startSeptember 22, 2022
Project endJune 30, 2027
Funding year2026
Award (this year)$107,897
NIH project number3U24HG012674-05S2
Project IDNIH-11599438 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to direct patient participation; this is a data/resource and coordination grant.

Less likely to help

Direct patient participation is not involved in this grant.

What this research studies

This grant supports creating a data resource and coordination center to enable a consortium studying what happens to cells when specific human genes are disabled. It focuses on making data findable, accessible, interoperable, and reusable, and on coordinating multiple research centers. The aim is to connect molecular signals with cellular outcomes in disease-relevant models, helping researchers understand gene functions and how they relate to human health.

Why it matters

Potential benefit: If successful, patients could benefit from faster, more accurate discoveries about how genes influence disease and potential new targets for therapies.

How similar studies have gone: Prior large-scale gene-function projects have shown that systematic, well-curated data accelerates discovery, though this exact MorPhiC approach is an emerging effort.

Where this research is happening

  • University of Miami School of Medicine
    Coral Gables, United States
    Active

Researchers

  • Principal investigator: Schurer, Stephan C — University of Miami School of Medicine
  • Study coordinator: Schurer, Stephan C

Related research

Other NIH-funded projects on the same topics.

  • Decoding how GAA repeats in FGF14 cause SCA27B

    This project looks at why a specific DNA repeat in the FGF14 gene leads to Spinocerebellar Ataxia 27B in adults.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11630855

  • Breathing therapy to help clear brain toxins in older adults who sleep poorly

    A small study will test a breathing-based therapy to boost brain toxin clearance in older adults with poor sleep patterns related to Alzheimer’s risk.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11617740

  • New retinal imaging to detect brain small vessel disease

    A fast, wide-field eye imaging method will measure how tiny retinal blood vessels rhythmically flow to help detect early brain small vessel disease.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11607100

  • Understanding the Genetics Behind IBD in South Florida

    This grant looks at how genes and the environment come together to influence inflammatory bowel disease in people living in South Florida.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11601644

  • MorPhiC data hub for gene function in human cells

    A data resource and coordinating center will organize and share information about how human genes affect cellular traits when knocked out, helping researchers understand gene functions.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11599437

  • Understanding Alzheimer's Genetic Risk in African and Admixed African-American People

    A study looks at genetic factors and biomarkers to understand why Alzheimer's disease affects African and admixed African-American communities differently.

    NIH research University of Miami School of Medicine · Coral Gables, United States · NIH-11595891

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.