Modernizing Gynecologic Cancer Trial Rules to Enroll More Patients
Official title: Modernizing Gynecologic Cancer Clinical Trial Eligibility Criteria to Increase Enrollment and Improve Generalizability
Funded at Ohio State University · NIH-11267497 · Data updated 2026-11-12
Aims to make gynecologic cancer clinical trials more accessible to diverse patients so more people can benefit from new treatments.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | August 5, 2026 |
| Project end | December 31, 2030 |
| Funding year | 2026 |
| Award (this year) | $775,836 |
| NIH project number | 1R01MD021198-01 |
| Project ID | NIH-11267497 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with gynecologic cancers who may be eligible for clinical trials and who belong to racial/ethnic minority groups (e.g., Asian, Black, Hispanic).
✕Less likely to help
Patients with cancers not covered by gynecologic trial criteria or those without access to participating sites may see no direct benefit.
What this research studies
This grant seeks to understand why minority patients with gynecologic cancers enroll in trials at lower rates and how trial eligibility criteria might be adjusted to be more inclusive. The team will study current protocol exclusions and experiment with changes that could broaden participation while maintaining safety. The goal is to improve generalizability of trial results and ensure diverse groups can access cutting-edge therapies in a real-world setting.
Why it matters
Potential benefit: If successful, more diverse patients could access clinical trials and benefit from new treatments.
How similar studies have gone: Prior work suggests minority patients enroll less often, but targeted changes to eligibility could improve participation and trial representativeness.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Felix, Ashley S. — Ohio State University
- Study coordinator: Felix, Ashley S.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.