Gynecologic cancer care: faster enrollment in targeted trials through molecular matching and better access to care
Official title: Gynecologic cancer care: Improving clinical trial enrollment through molecular matching with targeted therapies and improving access to care and research
Funded at Ohio State University · NIH-11416692 · Data updated 2026-11-12
Aims to speed up enrollment in personalized gynecologic cancer trials by matching patients to targeted therapies and improving access to care.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ohio State University NIH-funded |
| Lab location | 1 site (Columbus, UNITED STATES) |
| Project start | September 11, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $132,015 |
| NIH project number | 5R50CA287196-03 |
| Project ID | NIH-11416692 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with gynecologic cancers (especially endometrial/uterine cancers) who have actionable molecular subtypes and are candidates for clinical trials.
✕Less likely to help
Patients whose tumors lack targetable molecular features or who are not eligible for available trials may not benefit.
What this research studies
This project focuses on endometrial and other gynecologic cancers, using molecular profiles to pair patients with trials that target their tumor’s specific abnormalities. Working with OSU’s cancer center, the team will build a system to match patients to appropriate molecularly driven trials and remove barriers to participating. The effort includes coordinating care pathways, expanding access across populations, and partnering with national networks to boost trial accrual. The goal is to help patients get effective, personalized treatments faster while reducing unnecessary exposure to ineffective therapies.
Why it matters
Potential benefit: If successful, more gynecologic cancer patients could access promising targeted trials and receive therapies tailored to their tumor biology.
How similar studies have gone: Prior efforts show that molecular matching can improve trial enrollment and access, though challenges in accrual remain for rare subtypes.
Where this research is happening
-
Ohio State University
Columbus, United States Active
Researchers
- Principal investigator: Backes, Floor J. — Ohio State University
- Study coordinator: Backes, Floor J.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.