NIH-funded research NIH-funded research

Modeling how nicotine addiction develops in youth and its future impact

Official title: Modeling the Process of Nicotine Addiction among Youths and Young Adults and Its Potential Future Consequences

Funded at University of Michigan at Ann Arbor · NIH-11421857 · Data updated 2026-11-12

A program at the University of Michigan plans to use a computer model to understand how teens and young adults become addicted to nicotine and what might happen in the future under different regulations.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startSeptember 14, 2018
Project endAugust 31, 2028
Funding year2026
Award (this year)$425,244
NIH project number5U54CA229974-09
Project IDNIH-11421857 on NIH RePORTER

Who could benefit from this research

Could help

Not applicable to patients directly; the study uses a model of adolescent and young adult behavior rather than recruiting participants.

Less likely to help

No direct patient participation or benefit from this specific project.

What this research studies

This project builds a novel computer model that combines environmental, social, and biological factors to simulate how adolescents and young adults might start or quit using nicotine. The model will help explore how different nicotine product mixes and regulatory actions could influence addiction pathways and short-term outcomes. It will also project long-term consequences like deaths and life-years lost due to tobacco and nicotine dependence.

Why it matters

Potential benefit: If successful, this work could inform policies to reduce teen nicotine addiction and its long-term health harms.

How similar studies have gone: Prior research has used agent-based modeling to study addiction, with mixed but informative results guiding policy discussions.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Mendez Emilien, David — University of Michigan at Ann Arbor
  • Study coordinator: Mendez Emilien, David

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.