NIH-funded research NIH-funded research

Yale center researching how tobacco products affect use and addiction in people

Official title: Yale Center for the Study of Tobacco Product Use and Addiction (YCSTP)

Funded at Yale University · NIH-11533172 · Data updated 2026-11-12

A Yale research center is studying how nicotine, flavor additives, and other ingredients in tobacco products influence people’s likelihood of starting and becoming addicted.

More Addiction research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startSeptember 30, 2013
Project endAugust 31, 2028
Funding year2026
Award (this year)$38,427
NIH project number3U54DA036151-14S1
Project IDNIH-11533172 on NIH RePORTER

Who could benefit from this research

Could help

Ideal participants include adolescents and adults who use or are at risk of using tobacco products, as well as individuals contributing biological samples for analyses.

Less likely to help

Individuals not exposed to tobacco products or who are not part of the study design may not receive direct benefits.

What this research studies

This program brings together experts to explore how different nicotine forms and flavor compounds in tobacco products affect initiation and addiction across ages. Researchers will examine odorless cooling flavors, sweeteners, humectants, and nicotine stereoisomers delivered through various product types. The goal is to generate scientific evidence that can inform FDA regulatory decisions to reduce appeal and harm from tobacco products. The work involves complex studies with human-relevant data and may include analyses of human behavior and biological markers related to tobacco use.

Why it matters

Potential benefit: If successful, findings could strengthen regulations that reduce tobacco appeal and addiction, helping prevent initiation and support harm reduction.

How similar studies have gone: Past studies have shown that flavorings and nicotine formulations can influence appeal and addiction, supporting the potential impact of this line of research.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Krishnan-Sarin, Suchitra — Yale University
  • Study coordinator: Krishnan-Sarin, Suchitra

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.