Missed Pediatric Priority in Kidney Transplantation
Official title: Dissecting Missed Pediatric Priority in Kidney Transplantation
Funded at Indiana University Indianapolis · NIH-11430113 · Data updated 2026-11-12
This research aims to improve outcomes for children with kidney disease by focusing on when and how kidney transplantation can best help young patients.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Indiana University Indianapolis NIH-funded |
| Lab location | 1 site (Indianapolis, United States) |
| Project start | August 15, 2026 |
| Project end | April 30, 2031 |
| Funding year | 2026 |
| Award (this year) | $695,538 |
| NIH project number | 1R01DK148707-01 |
| Project ID | NIH-11430113 on NIH RePORTER |
Who could benefit from this research
✓Could help
Children and adolescents with chronic kidney disease, especially those approaching end-stage kidney disease or considering transplantation.
✕Less likely to help
Patients with CKD who are managed without transplantation or have conditions unlikely to benefit from kidney replacement therapy may see limited direct impact.
What this research studies
This project looks at pediatric chronic kidney disease and the role of kidney transplantation to reduce cardiovascular risk and improve growth and development. It considers age ranges from infancy to young adulthood and how different disease origins affect transplant timing and outcomes. The study will analyze pediatric CKD patients, look at transplant timing, and explore factors that influence survival and quality of life after transplant. By understanding missed opportunities for timely transplantation, clinicians can make better-informed decisions for children and their families.
Why it matters
Potential benefit: If successful, the work could lead to earlier, more effective use of kidney transplantation in children and better long-term health and quality of life for pediatric patients with kidney disease.
How similar studies have gone: Prior studies show that transplant can markedly reduce cardiovascular risk and improve survival compared with dialysis in pediatric patients.
Where this research is happening
-
Indiana University Indianapolis
Indianapolis, United States Active
Researchers
- Principal investigator: Laster, Marciana Lee — Indiana University Indianapolis
- Study coordinator: Laster, Marciana Lee
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.