NIH-funded research U01 cooperative agreement

Military Service–Linked ALS Risk in U.S. Veterans

Official title: Military Service-Associated ALS Risk Factor Study Among U.S. Veterans

Funded at Seattle Inst for Biomedical/clinical Res · NIH-11565245 · Data updated 2026-11-12

This NIH grant investigates why U.S. veterans get ALS more often, by studying military exposures and health records to identify potential risk factors.

Quick facts

Grant typeU01 cooperative agreement
Study typeNIH-funded research
Funding institutionSeattle Inst for Biomedical/clinical Res
NIH-funded
Lab location1 site (Seattle, United States)
Project startSeptember 30, 2026
Project endSeptember 29, 2029
Funding year2026
Award (this year)$298,151
NIH project number1U01TS000354-01
Project IDNIH-11565245 on NIH RePORTER

Who could benefit from this research

Could help

Veterans who served in the military and may eventually develop or have ALS could be relevant, especially those with exposure histories.

Less likely to help

Individuals without military exposure history or ALS are less likely to benefit directly.

What this research studies

This project uses VA health data to compare veterans with ALS to similar veterans without ALS, looking at exposures like burn pits, herbicides, and brain injuries. Researchers will link large health and exposure datasets to create the largest records-based study of military ALS risk factors. The aim is to clarify how service-related factors may contribute to ALS and to identify possible high-risk groups for future prevention efforts.

Why it matters

Potential benefit: Understanding military-related factors that increase ALS risk could lead to better prevention and earlier identification for veterans.

How similar studies have gone: Previous studies were small; this effort aims to provide a much larger, more definitive analysis using linked records.

Where this research is happening

  • Seattle Inst for Biomedical/clinical Res
    Seattle, United States
    Active

Researchers

  • Principal investigator: Howard, Ileana — Seattle Inst for Biomedical/clinical Res
  • Study coordinator: Howard, Ileana

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About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.