NIH-funded research R01 grant

Mental Wellness Coordinated Care for Young People with Untreated Psychosis in Mozambique

Official title: Mental Wellness Coordinated Specialty Care (mWell-CSC) in Mozambique: Implementing evidence-based early intervention services for young people with untreated psychosis

Funded at New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC · NIH-11535217 · Data updated 2026-11-12

A program in Mozambique aims to bring early, coordinated care for adolescents and young adults with new psychosis, using evidence-based services to reduce symptoms and improve functioning.

More Psychosis research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionNew York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
NIH-funded
Lab location1 site (New York, United States)
Project startAugust 6, 2026
Project endJuly 31, 2031
Funding year2026
Award (this year)$185,959
NIH project number3R01MH138802-01S1
Project IDNIH-11535217 on NIH RePORTER

Who could benefit from this research

Could help

Young people aged approximately 15–24 in Mozambique with new-onset, non-substance-induced psychosis.

Less likely to help

Individuals without psychosis or with long-standing, previously treated illness may see little direct benefit.

What this research studies

This project adapts Coordinated Specialty Care to a low-resource setting in Mozambique, focusing on young people with first-episode psychosis who have not yet received treatment. It will blend medication management with psychosocial support and use technology to screen and engage communities. The team will partner with local mental health services to implement early intervention strategies that fit the local context, aiming to shorten the time before treatment starts and keep young people engaged in care.

Why it matters

Potential benefit: If successful, this approach could shorten delays to treatment, reduce relapses, and help young people return to school or work.

How similar studies have gone: Previous CSC programs in high-income countries show promise, but this is a novel adaptation for LMIC settings.

Where this research is happening

  • New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
    New York, United States
    Active

Researchers

  • Principal investigator: Wainberg, Milton L — New York State Psychiatric Institute Dba Research Foundation for Mental Hygiene, INC
  • Study coordinator: Wainberg, Milton L

Related research

Other NIH-funded projects on the same topics.

  • Psychosis in diverse settings across the world

    This project studies how psychotic disorders show up and respond to treatment in adults with diverse backgrounds, including populations in Africa, the Caribbean, and other Global South settings.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-11592428

  • Psychosis in Diverse Settings: Understanding Symptoms and Treatment Across Global South

    A human-facing study will look at how psychotic disorders present and respond to treatment in adults from Africa, the Caribbean, and other Global South settings, using genetic and clinical data.

    NIH research Suny Downstate Medical Center · Brooklyn, United States · NIH-11592427

  • A new online brain-scan-style tool to spot early psychosis risk

    A new online-based set of tasks and a computer model aims to identify people at high risk for developing psychosis earlier and more accurately.

    NIH research Northwestern University · Chicago, United States · NIH-11590585

  • Genetic clues for early-onset psychosis in Latino youth

    This project looks at the genes of young people with early-onset psychosis and compares them with similar youths without psychosis to find genetic factors that contribute to the illness.

    NIH research Boston Children's Hospital · Boston, United States · NIH-11554752

  • Biomarkers to tailor rehab for Veterans with schizophrenia

    A clinician-scientist is developing a brain-based biomarker to guide personalized rehabilitation for Veterans with schizophrenia.

    NIH research VA San Diego Healthcare System · San Diego, United States · NIH-11552825

  • Computational analysis of facial expression in early psychosis

    Aims to develop computer-based measures of facial expression in people at risk for or with schizophrenia to help track symptoms and guide future trials.

    NIH research Icahn School of Medicine at Mount Sinai · New York, United States · NIH-11539126

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.