MDSRC Administrative Core supports muscular dystrophy therapies
Official title: MDSRC Administrative Core
Funded at Research Inst Nationwide Children's Hosp · NIH-11397441 · Data updated 2026-11-12
This grant supports a center that accelerates therapies for muscular dystrophy, including Duchenne and LGMD2I, by sharing expertise and coordinating projects across teams.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Research Inst Nationwide Children's Hosp NIH-funded |
| Lab location | 1 site (Columbus, United States) |
| Project start | August 15, 2024 |
| Project end | July 31, 2028 |
| Funding year | 2026 |
| Award (this year) | $140,894 |
| NIH project number | 5P50HD117373-03 |
| Project ID | NIH-11397441 on NIH RePORTER |
Who could benefit from this research
✓Could help
Patients with muscular dystrophy, especially Duchenne muscular dystrophy (DMD) and LGMD2I, and their families, who may participate in future trials or biomarker studies.
✕Less likely to help
Patients not affected by muscular dystrophy or not eligible for the specific study components may not benefit.
What this research studies
The MDSRC Administrative Core brings together experts from Nationwide Children’s Hospital and OSU/NCH to advance gene therapy approaches for muscular dystrophy. It provides shared resources and coordination to push promising therapies from the lab toward patients. The projects aim to develop new vectors, restore dystrophin expression, and identify biomarkers to track disease and treatment responses. The center emphasizes collaboration with patient communities and translation from bench to bedside.
Why it matters
Potential benefit: If successful, patients with muscular dystrophy could see faster development of effective gene therapies and better ways to monitor disease progress.
How similar studies have gone: Past gene therapy efforts in muscular dystrophy have shown promise, with ongoing work moving toward clinical applications.
Where this research is happening
-
Research Inst Nationwide Children's Hosp
Columbus, United States Active
Researchers
- Principal investigator: Flanigan, Kevin M — Research Inst Nationwide Children's Hosp
- Study coordinator: Flanigan, Kevin M
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.