Malaria surveillance and resistance research in Uganda to fight artemisinin resistance and transmission
Official title: Program for Resistance, Immunology, Surveillance & Modeling of Malaria in Uganda (PRISM) Renewal
Funded at University of California, San Francisco · NIH-11518108 · Data updated 2026-11-12
A U19 program in Uganda studies malaria, drug and insecticide resistance, and surveillance to help reduce illness and deaths from malaria in Africa.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project start | July 1, 2010 |
| Project end | April 30, 2029 |
| Funding year | 2026 |
| Award (this year) | $590,328 |
| NIH project number | 3U19AI089674-17S1 |
| Project ID | NIH-11518108 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are individuals in malaria-endemic areas in Uganda, particularly children under 11, who may benefit from improved diagnosis, treatment options, and public health interventions.
✕Less likely to help
Patients in areas outside the study region or without access to updated control measures may see limited direct benefit.
What this research studies
This project partners with Uganda to monitor malaria patterns, track how well control measures work, and study resistance to drugs and insecticides. It combines facility-based surveillance, longitudinal studies, and lab work to measure drug resistance markers and exposure to malaria. The goal is to generate data that can guide better prevention and treatment strategies for communities affected by malaria in Africa. The program builds on existing networks to strengthen malaria surveillance and response in a high-burden setting.
Why it matters
Potential benefit: Improved understanding of malaria trends and resistance could lead to more effective treatments and control strategies for patients and communities.
How similar studies have gone: Prior malaria surveillance and resistance studies have informed policy and practice in similar settings, though ongoing challenges remain due to resistance and transmission dynamics.
Where this research is happening
-
University of California, San Francisco
San Francisco, United States Active
Researchers
- Principal investigator: Dorsey, Matthew G — University of California, San Francisco
- Study coordinator: Dorsey, Matthew G
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.