NIH-funded research NIH-funded research

Low-energy skin radiation patches for treating non-melanoma skin cancer

Official title: Activated GaP-32 for the Treatment of Non-Melanoma Skin Cancer

Funded at Oncopatch, INC · NIH-11314378 · Data updated 2026-11-12

A patient-friendly device idea uses a patch to deliver a tiny amount of radiation right at the skin to treat non-melanoma skin cancer in as few visits.

More Melanoma research and trials

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionOncopatch, INC
NIH-funded
Lab location1 site (Centennial, United States)
Project startSeptember 7, 2026
Project endAugust 31, 2027
Funding year2026
Award (this year)$305,893
NIH project number1R41CA310335-01
Project IDNIH-11314378 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adults with non-melanoma skin cancer lesions suitable for surface radiation therapy and who can follow-up for treatment evaluation.

Less likely to help

Patients with deeply invasive skin cancers or lesions not appropriate for surface patch therapy may not benefit from this approach.

What this research studies

This project explores a patch-like device that emits low-energy beta radiation from Phosphorus-32 to treat skin cancers on the surface of the skin. The goal is to provide effective treatment with highly localized dosing, potentially reducing the need for multiple clinic visits. Researchers will test GaP-32 patches and study how well they hold and deliver the radiation safely in a controlled setting. The work involves collaboration between OncoPatch, Colorado School of Mines, and University of Colorado, focusing on making the patch reliable and biocompatible for skin treatment.

Why it matters

Potential benefit: If successful, patients with non-melanoma skin cancer could receive effective treatment in fewer sessions with less impact on daily life.

How similar studies have gone: Prior attempts at patch-based or surface-localized radiation have shown promise, but this specific GaP-32 patch approach is novel.

Where this research is happening

  • Oncopatch, INC
    Centennial, United States
    Active

Researchers

  • Principal investigator: Sarazin, Fred — Oncopatch, INC
  • Study coordinator: Sarazin, Fred

Related research

Other NIH-funded projects on the same topics.

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  • MOSAIC II: MAP Wound Matrix to speed graft readiness after non-melanoma skin cancer surgery

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    NIH research Tempo Therapeutics, INC. · San Diego, UNITED STATES · NIH-11406980

  • Safer medicines to prevent basal and squamous (non‑melanoma) skin cancer

    Researchers are developing new, non‑toxic oral rexinoid medicines aimed at preventing basal cell and squamous cell skin cancers, especially for people with weakened immune systems like organ transplant recipients.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11289434

  • Creating safe drugs to prevent non-melanoma skin cancer

    This study is working on new medications to help prevent skin cancer in people with weakened immune systems, like those who have had organ transplants, by creating safer and more effective options that don’t have the usual side effects of current treatments.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11015805

  • New ways to prevent non-melanoma skin cancer

    This study is looking for new ways to help prevent non-melanoma skin cancers, like basal cell and squamous cell carcinoma, by understanding how these cancers develop and testing new treatments that could lower your risk.

    NIH research University of Arizona · Tucson, United States · NIH-10686365

  • Advancing Treatments for Melanoma and Skin Cancer

    This program is looking for new and better ways to treat melanoma and other skin cancers, especially when current treatments aren't enough.

    NIH research University of Pittsburgh at Pittsburgh · Pittsburgh, United States · NIH-11187069

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.