New ways to prevent non-melanoma skin cancer
Official title: Targeted Prevention for Non-Melanoma Skin Cancer
Funded at University of Arizona · NIH-10686365 · Data updated 2026-11-12
This study is looking for new ways to help prevent non-melanoma skin cancers, like basal cell and squamous cell carcinoma, by understanding how these cancers develop and testing new treatments that could lower your risk.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Arizona NIH-funded |
| Lab location | 1 site (Tucson, United States) |
| Project start | September 10, 2019 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $1,301,234 |
| NIH project number | 5P01CA229112-05 |
| Project ID | NIH-10686365 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals at high risk for non-melanoma skin cancer, such as those with a history of skin lesions or significant sun exposure.
✕Less likely to help
Patients who have already been diagnosed with advanced non-melanoma skin cancer may not benefit from this preventive research.
What this research studies
This research focuses on developing targeted prevention strategies for non-melanoma skin cancer, which includes basal cell carcinoma and squamous cell carcinoma. The project aims to understand the biological pathways involved in skin cancer development and to create new drugs that can prevent these cancers from forming. By using experimental models and human studies, the researchers will explore how specific molecular targets can be effectively modulated to reduce the risk of skin cancer. Patients may benefit from innovative treatments that could significantly lower their chances of developing these common skin cancers.
Why it matters
Potential benefit: If successful, this research could lead to effective prevention strategies that significantly reduce the incidence of non-melanoma skin cancer.
How similar studies have gone: Previous research has shown promise in targeting specific molecular pathways for cancer prevention, indicating that this approach could be effective.
Where this research is happening
-
University of Arizona
Tucson, United States Active
Researchers
- Principal investigator: Curiel-Lewandrowski, Clara — University of Arizona
- Study coordinator: Curiel-Lewandrowski, Clara
Related research
Other NIH-funded projects on the same topics.
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CivaDerm: a new four-day skin cancer radiation bandage
A new four‑day radiation bandage for non-melanoma skin cancer aims to treat facial and other areas without multiple clinic visits or big scars.
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MOSAIC II: MAP Wound Matrix to speed graft readiness after non-melanoma skin cancer surgery
A randomized trial tests a moldable wound scaffold (MAP Wound Matrix) to speed healing and time to graft-ready skin after head and neck cancer surgeries in adults.
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Low-energy skin radiation patches for treating non-melanoma skin cancer
A patient-friendly device idea uses a patch to deliver a tiny amount of radiation right at the skin to treat non-melanoma skin cancer in as few visits.
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Safer medicines to prevent basal and squamous (non‑melanoma) skin cancer
Researchers are developing new, non‑toxic oral rexinoid medicines aimed at preventing basal cell and squamous cell skin cancers, especially for people with weakened immune systems like organ transplant recipients.
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Creating safe drugs to prevent non-melanoma skin cancer
This study is working on new medications to help prevent skin cancer in people with weakened immune systems, like those who have had organ transplants, by creating safer and more effective options that don’t have the usual side effects of current treatments.
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Advancing Treatments for Melanoma and Skin Cancer
This program is looking for new and better ways to treat melanoma and other skin cancers, especially when current treatments aren't enough.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.