NIH-funded research R01 grant

Long-term study of how pesticide exposure affects fertility and hormones from adolescence to young adulthood

Official title: The ESPINA Study 19th Year Follow-Up: A Longitudinal Investigation of Pesticide Exposures in relation to Fertility and Hormonal Health

Funded at University of California, San Diego · NIH-11419583 · Data updated 2026-11-12

This study follows people in Ecuador from adolescence into their twenties to see how pesticide exposure may influence fertility and hormone health.

More Fertility research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of California, San Diego
NIH-funded
Lab location1 site (La Jolla, United States)
Project startSeptember 18, 2020
Project endJune 30, 2030
Funding year2026
Award (this year)$467,802
NIH project number5R01ES030378-07
Project IDNIH-11419583 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are adolescents or young adults aged around 12–27 who have been part of the ESPINA cohort and have stored biospecimens with exposure data.

Less likely to help

Participants not exposed to pesticides or not progressing into reproductive years may have limited direct benefit.

What this research studies

Participants are followed over time to measure reproductive health biomarkers using collected biospecimens and exposure data. The project uses biomarker measurements to track pesticide exposure and links these data to fertility and endocrine health outcomes as participants reach peak reproductive years. Based at UC San Diego, the study builds on the ESPINA cohort to provide deeper insights into how environmental factors shape reproductive health for young people and adults.

Why it matters

Potential benefit: Better understanding of how pesticides affect fertility and hormonal health could inform public health guidelines and prevention strategies.

How similar studies have gone: Previous ESPINA follow-ups have shown meaningful associations; this longitudinal approach aims to strengthen evidence with biomarker data.

Where this research is happening

  • University of California, San Diego
    La Jolla, United States
    Active

Researchers

  • Principal investigator: Suarez, Jose Ricardo — University of California, San Diego
  • Study coordinator: Suarez, Jose Ricardo

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.