NIH-funded research R01 grant

Long-term health effects for moms and babies after COVID during pregnancy

Official title: Long term adverse health outcomes for women and children following SARS-CoV-2 infection during pregnancy

Funded at Kaiser Foundation Research Institute · NIH-11361138 · Data updated 2026-11-12

This grant study follows pregnant people and their children to understand long-term health effects after SARS-CoV-2 infection during pregnancy.

More Pregnancy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionKaiser Foundation Research Institute
NIH-funded
Lab location1 site (Oakland, UNITED STATES)
Project startJuly 1, 2023
Project endJune 30, 2028
Funding year2026
Award (this year)$825,518
NIH project number5R01AI178009-04
Project IDNIH-11361138 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates are pregnant people with access to Kaiser Permanente health records and their children up to several years of age, especially those with documented SARS-CoV-2 infection during pregnancy.

Less likely to help

Patients without access to the participating health system records or without SARS-CoV-2 infection during pregnancy may see limited direct benefit.

What this research studies

Researchers will use Kaiser Permanente’s electronic health records to track outcomes in a large cohort of pregnant people and their children over time, focusing on cardiometabolic and neuropsychiatric health for mothers and growth and development for children. The study will look at how outcomes vary by virus variants and vaccination status, while accounting for pre-existing health conditions. By following more than 195,000 pregnancies, the project aims to identify long-term risks and potential protective factors to inform care during and after pregnancy.

Why it matters

Potential benefit: If successful, findings could guide better monitoring and interventions for pregnant people and their children exposed to SARS-CoV-2.

How similar studies have gone: There is emerging evidence of long-term effects, but this study expands follow-up and variant-specific insights in a large, real-world pregnant population.

Where this research is happening

  • Kaiser Foundation Research Institute
    Oakland, United States
    Active

Researchers

  • Principal investigator: Hedderson, Monique Marie — Kaiser Foundation Research Institute
  • Study coordinator: Hedderson, Monique Marie

Related research

Other NIH-funded projects on the same topics.

  • Understanding how COVID-19 during pregnancy affects infant brain development

    This study is looking at how a mother's COVID-19 infection during pregnancy might affect her baby's brain development and health as they grow, so we can better understand any risks and help families in the future.

    NIH research Lurie Children's Hospital of Chicago · Chicago, United States · NIH-11139564

  • Effects of COVID-19 on pregnancy and maternal health outcomes

    This study is looking at how COVID-19 and its effects on health might impact pregnancy and the health of mothers and babies, especially for those facing challenges in healthcare, to help improve outcomes for everyone during and after pregnancy.

    NIH research Medical University of South Carolina · Charleston, United States · NIH-11136605

  • Understanding long-term health effects of COVID-19 during pregnancy on mothers and children

    This project looks at how COVID-19 infection during pregnancy might affect the long-term health of mothers and their children.

    NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-11129770

  • Long-term health effects of COVID-19 on pregnant women and their children

    This study is looking at how COVID-19 during pregnancy affects the health of moms and their babies over time, focusing on things like heart health and mental well-being, so we can better understand the long-term impacts for families.

    NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-10873260

  • Effects of COVID-19 on pregnancy and maternal health outcomes

    This study looks at how COVID-19 and the virus that causes it have impacted pregnancy and the health of mothers and babies, especially considering the challenges some people face in getting good healthcare during the pandemic.

    NIH research Medical University of South Carolina · Charleston, United States · NIH-10817936

  • How COVID-19 infection and genes may influence memory and dementia risk

    This study looks at how getting COVID-19 and a person’s genes together affect the chance of developing memory problems and Alzheimer’s disease later in life.

    NIH research University of Texas Hlth Science Center · San Antonio, United States · NIH-11617103

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.