NIH-funded research R01 grant

Effects of COVID-19 on pregnancy and maternal health outcomes

Official title: Impact of the COVID-19 pandemic, SARS-CoV-2 infection and social determinants of health on pregnancy complications, birth outcomes and post-pregnancy maternal cardiovascular and mortality outcomes

Funded at Medical University of South Carolina · NIH-11136605 · Data updated 2026-11-12

This study is looking at how COVID-19 and its effects on health might impact pregnancy and the health of mothers and babies, especially for those facing challenges in healthcare, to help improve outcomes for everyone during and after pregnancy.

More Pregnancy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startApril 1, 2022
Project endMarch 31, 2026
Funding year2024
Award (this year)$68,657
NIH project number3R01HL163963-03S1
Project IDNIH-11136605 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include pregnant individuals who have been infected with SARS-CoV-2 or are affected by social determinants of health.

Less likely to help

Patients who are not pregnant or those who have not been exposed to COVID-19 may not receive benefits from this research.

What this research studies

This research investigates how the COVID-19 pandemic and SARS-CoV-2 infection affect pregnancy complications and outcomes for mothers and infants. It focuses on understanding the role of social determinants of health and healthcare inequities that have been exacerbated by the pandemic. The study aims to gather data on maternal cardiovascular health and mortality rates, particularly in populations that experience significant disparities. By analyzing these factors, the research seeks to provide insights into improving maternal and infant health during and after pregnancy.

Why it matters

Potential benefit: If successful, this research could lead to improved healthcare strategies and interventions for pregnant individuals, particularly those affected by COVID-19.

How similar studies have gone: Other research has indicated significant impacts of viral infections on pregnancy outcomes, suggesting that this study's approach is relevant and necessary.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Malek, Angela M — Medical University of South Carolina
  • Study coordinator: Malek, Angela M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.