NIH-funded research R01 grant

Effects of COVID-19 on pregnancy and maternal health outcomes

Official title: Impact of the COVID-19 pandemic, SARS-CoV-2 infection and social determinants of health on pregnancy complications, birth outcomes and post-pregnancy maternal cardiovascular and mortality outcomes

Funded at Medical University of South Carolina · NIH-10817936 · Data updated 2026-11-12

This study looks at how COVID-19 and the virus that causes it have impacted pregnancy and the health of mothers and babies, especially considering the challenges some people face in getting good healthcare during the pandemic.

More Pregnancy research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionMedical University of South Carolina
NIH-funded
Lab location1 site (Charleston, United States)
Project startApril 1, 2022
Project endMarch 31, 2026
Funding year2024
Award (this year)$481,842
NIH project number5R01HL163963-03
Project IDNIH-10817936 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include pregnant individuals who have been infected with SARS-CoV-2 or are affected by social determinants of health.

Less likely to help

Patients who are not pregnant or those who have not been affected by COVID-19 may not receive benefits from this research.

What this research studies

This research investigates how the COVID-19 pandemic and SARS-CoV-2 infection affect pregnancy complications and outcomes for both mothers and infants. It focuses on understanding the role of social determinants of health and healthcare disparities that have been exacerbated by the pandemic. The study will analyze data on maternal cardiovascular health, pregnancy complications like pre-eclampsia, and adverse birth outcomes such as preterm birth. By examining these factors, the research aims to provide insights into improving maternal and infant health during and after the pandemic.

Why it matters

Potential benefit: If successful, this research could lead to improved healthcare strategies and interventions that enhance maternal and infant health outcomes during and after pregnancy.

How similar studies have gone: Other research has shown that understanding the impacts of infectious diseases on pregnancy can lead to significant improvements in maternal and infant health outcomes, indicating that this approach has potential for success.

Where this research is happening

  • Medical University of South Carolina
    Charleston, United States
    Active

Researchers

  • Principal investigator: Malek, Angela M — Medical University of South Carolina
  • Study coordinator: Malek, Angela M

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.