Kids First Pediatric Data Resource Center accelerates collaborative data discovery for childhood development and cancer
Official title: Gabriella Miller Kids First Pediatric Data Resource Center: Advancing Collaborative Platform-Enabled Data-Driven Discovery at the Intersection of Childhood Development and Cancer
Funded at Children's Hosp of Philadelphia · NIH-11551698 · Data updated 2026-11-12
A large, openly shared collection of kids’ genomic and clinical data is being expanded to help researchers uncover better ways to understand and treat childhood diseases including cancer.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Children's Hosp of Philadelphia NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2026 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $4,000,000 |
| NIH project number | 3U2CHD109731-08S5 |
| Project ID | NIH-11551698 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates are children with cancer or congenital conditions whose genomic and clinical data may contribute to research resources (through data sharing and future possible studies).
✕Less likely to help
Patients whose data are not included or whose conditions are not studied may not receive direct benefits from this project.
What this research studies
If you or your child has a pediatric cancer or developmental condition, this project builds and shares massive genomic and clinical data from many children to help scientists find patterns. It adds new cloud-based tools and workflows to release more data, integrate clinical submissions, and prepare data for AI and machine learning analyses. The goal is to enable researchers to quickly assemble cohorts, analyze complex data, and generate insights that could guide future treatments and care. This is a data-resource project designed to empower many researchers to collaborate and accelerate discoveries that could benefit pediatric patients.
Why it matters
Potential benefit: Ultimately, it could lead to faster, more personalized insights and improvements in diagnosis and treatment for children with cancer or developmental conditions.
How similar studies have gone: Previous Kids First data resources have enabled large-scale analyses and collaborative discoveries in pediatric health.
Where this research is happening
-
Children's Hosp of Philadelphia
Philadelphia, United States Active
Researchers
- Principal investigator: Resnick, Adam Cain — Children's Hosp of Philadelphia
- Study coordinator: Resnick, Adam Cain
Related research
Other NIH-funded projects on the same topics.
-
Emotional and biobehavioral links in parent-infant closeness
A program to understand how parent and baby feel and react to each other in early life, with the goal of guiding better child social and emotional development.
-
Leukodystrophy Clinical Careers and Mentorship Network
A program to train, mentor, and support clinicians and researchers to advance care for people with leukodystrophies.
-
Role of ATP1A3 mutations in sudden death related to epilepsy
Aims to understand how ATP1A3 gene changes may lead to sudden death in kids with epilepsy and is exploring new ways to prevent it.
-
Kids First Data Resource Center: cloud-enabled data sharing for childhood cancer research
A data resource project that makes pediatric cancer data and analyses more accessible to researchers, with the goal of advancing understanding and care for children with cancer.
-
PROMISE: A Network for Real-World Evidence in Rare Pediatric Cancers
A network will collect and harmonize pediatric cancer patient records from multiple centers to create high-quality real-world data that can support quicker, regulatory-ready insights when randomized trials aren’t feasible.
-
Data Hub Core for Down syndrome research
A data hub project is building a big, interoperable platform to securely share and analyze information from people with Down syndrome and related conditions.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.