NIH-funded research NIH-funded research

Investigating visual perception issues in children with amblyopia

Official title: Spatial Frequency Dependent Deficits in Anisometropic Amblyopia

Funded at Boston Children's Hospital · NIH-10909973 · Data updated 2026-11-12

This study is looking at how kids with anisometropic amblyopia see things differently, especially when it comes to recognizing patterns and contrasts, and it aims to learn more about their vision challenges through fun visual tests and advanced imaging techniques.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionBoston Children's Hospital
NIH-funded
Lab location1 site (Boston, United States)
Project startSeptember 30, 2022
Project endNovember 30, 2027
Funding year2024
Award (this year)$142,669
NIH project number5K23EY034212-03
Project IDNIH-10909973 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are children diagnosed with anisometropic amblyopia.

Less likely to help

Patients with other types of amblyopia or those without visual perception issues may not benefit from this research.

What this research studies

This research focuses on understanding how visual perception, specifically spatial frequency and contrast sensitivity, is affected in children with anisometropic amblyopia. By employing advanced neuroimaging techniques and psychophysical assessments, the study aims to explore the underlying mechanisms of visual deficits caused by interocular inhibition. The research will involve training in experimental design and data analysis to develop new insights into pediatric vision disorders. Participants may undergo various visual tests to help validate the findings.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic and treatment strategies for children with amblyopia.

How similar studies have gone: Previous research has shown promise in using neuroimaging and psychophysical methods to understand visual disorders, indicating that this approach could yield valuable insights.

Where this research is happening

  • Boston Children's Hospital
    Boston, United States
    Active

Researchers

  • Principal investigator: Wiecek, Emily — Boston Children's Hospital
  • Study coordinator: Wiecek, Emily

Related research

Other NIH-funded projects on the same topics.

  • High-resolution 7T fMRI to understand developmental causes of amblyopia

    This project uses ultra-high field brain imaging to learn how amblyopia develops in people, with an emphasis on how vision sources interact in early life.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11445359

  • A smart occlusion dose monitor to help kids with amblyopia wear patches

    A new device called AmblyoGo helps children with amblyopia wear their eye patches more consistently by automatically tracking patch wear and sharing simple feedback with families and clinicians.

    NIH research Edge Eye Labs INC. · San Francisco, United States · NIH-11410213

  • Better treatments for amblyopia (lazy eye) and binocular vision in children

    This compares a patch-free, activity-based therapy to standard eye patching to help children with amblyopia (lazy eye) improve vision and stick with treatment.

    NIH research Retina Foundation of the Southwest · Dallas, United States · NIH-11285476

  • How attention can change eye suppression in amblyopia (lazy eye)

    This project tests whether directing attention to the weaker eye can reduce visual suppression for adults with amblyopia (lazy eye).

    NIH research Smith-Kettlewell Eye Research Institute · San Francisco, United States · NIH-11285207

  • Understanding how attention affects vision in lazy eye

    This study is looking at how focusing your attention can help improve vision in adults with lazy eye, and it aims to find new ways to treat this condition by understanding how the brain works in these situations.

    NIH research Smith-Kettlewell Eye Research Institute · San Francisco, United States · NIH-11030313

  • Understanding depth perception in individuals with lazy eye

    This study is looking at how people with lazy eye see depth and if their side vision plays a role in that, with the goal of finding better ways to help improve their vision.

    NIH research Smith-Kettlewell Eye Research Institute · San Francisco, United States · NIH-10898776

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.