NIH-funded research R01 grant

Understanding how attention affects vision in lazy eye

Official title: Interocular Suppression and Selective Attention in Amblyopia

Funded at Smith-Kettlewell Eye Research Institute · NIH-11030313 · Data updated 2026-11-12

This study is looking at how focusing your attention can help improve vision in adults with lazy eye, and it aims to find new ways to treat this condition by understanding how the brain works in these situations.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSmith-Kettlewell Eye Research Institute
NIH-funded
Lab location1 site (San Francisco, United States)
Project startAugust 1, 2023
Project endFebruary 28, 2027
Funding year2025
Award (this year)$517,824
NIH project number5R01EY035346-03
Project IDNIH-11030313 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for participation include adults diagnosed with amblyopia who are experiencing visual suppression.

Less likely to help

Patients with amblyopia who do not have significant visual suppression or those with other unrelated visual impairments may not benefit from this research.

What this research studies

This research investigates how visual attention influences the suppression of vision in individuals with amblyopia, commonly known as lazy eye. It aims to understand the brain mechanisms involved in this condition by examining how selective attention can enhance visual responses from the preferred eye while suppressing the non-preferred eye. The study will utilize psychophysical methods and EEG imaging to assess the effects of attention and visual cues on perception in adults with amblyopia. By exploring these dynamics, the research seeks to identify potential new treatment strategies for amblyopia.

Why it matters

Potential benefit: If successful, this research could lead to improved treatment methods for amblyopia, enhancing visual outcomes for affected individuals.

How similar studies have gone: Previous research has shown promising results in understanding visual attention and suppression in amblyopia, suggesting that this approach may yield valuable insights.

Where this research is happening

  • Smith-Kettlewell Eye Research Institute
    San Francisco, United States
    Active

Researchers

  • Principal investigator: Hou, Chuan — Smith-Kettlewell Eye Research Institute
  • Study coordinator: Hou, Chuan

Related research

Other NIH-funded projects on the same topics.

  • High-resolution 7T fMRI to understand developmental causes of amblyopia

    This project uses ultra-high field brain imaging to learn how amblyopia develops in people, with an emphasis on how vision sources interact in early life.

    NIH research Massachusetts General Hospital · Boston, United States · NIH-11445359

  • A smart occlusion dose monitor to help kids with amblyopia wear patches

    A new device called AmblyoGo helps children with amblyopia wear their eye patches more consistently by automatically tracking patch wear and sharing simple feedback with families and clinicians.

    NIH research Edge Eye Labs INC. · San Francisco, United States · NIH-11410213

  • Better treatments for amblyopia (lazy eye) and binocular vision in children

    This compares a patch-free, activity-based therapy to standard eye patching to help children with amblyopia (lazy eye) improve vision and stick with treatment.

    NIH research Retina Foundation of the Southwest · Dallas, United States · NIH-11285476

  • How attention can change eye suppression in amblyopia (lazy eye)

    This project tests whether directing attention to the weaker eye can reduce visual suppression for adults with amblyopia (lazy eye).

    NIH research Smith-Kettlewell Eye Research Institute · San Francisco, United States · NIH-11285207

  • Investigating visual perception issues in children with amblyopia

    This study is looking at how kids with anisometropic amblyopia see things differently, especially when it comes to recognizing patterns and contrasts, and it aims to learn more about their vision challenges through fun visual tests and advanced imaging techniques.

    NIH research Boston Children's Hospital · Boston, United States · NIH-10909973

  • Understanding depth perception in individuals with lazy eye

    This study is looking at how people with lazy eye see depth and if their side vision plays a role in that, with the goal of finding better ways to help improve their vision.

    NIH research Smith-Kettlewell Eye Research Institute · San Francisco, United States · NIH-10898776

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.