Investigating how specific immune cells can effectively target and eliminate solid tumors
The Unique Roles of Tumor-Specific Th9 Cells for Solid Tumor Eradication
This study is looking at a special type of immune cell called Th9 cells to see how they can better fight solid tumors, with the hope that what they learn will help improve treatments for patients with cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Methodist Hospital Research Institute NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11084415 on NIH RePORTER |
What this research studies
This research focuses on a unique type of immune cell known as Th9 cells, which have shown promise in attacking solid tumors. The project aims to understand how these cells can penetrate tumor tissues and overcome challenges posed by the diversity of tumor antigens. By using advanced tumor models that mimic real clinical situations, the researchers will explore the mechanisms that allow Th9 cells to effectively kill cancer cells and prevent tumor recurrence. The findings could lead to improved adoptive cell therapies for patients with solid tumors.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients with advanced solid tumors who may benefit from innovative immunotherapy approaches.
Not a fit: Patients with non-solid tumors or those who do not respond to immunotherapy may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for patients with solid tumors, potentially improving survival rates and quality of life.
How similar studies have performed: Previous research has shown promise in using immune cells for cancer treatment, but the specific approach of targeting Th9 cells in solid tumors is relatively novel.
Where this research is happening
Houston, United States
- Methodist Hospital Research Institute — Houston, United States (Active)
Researchers
- Principal investigator: Lu, Yong — Methodist Hospital Research Institute
- Study coordinator: Lu, Yong
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.