Investigating how chronic epilepsy affects brain aging
PET/MR Correlates of Accelerated Aging in Chronic Epilepsy
This study is looking at how chronic epilepsy might speed up brain aging and is for people with epilepsy who want to understand how their condition could affect their brain health over time.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Wisconsin-Madison NIH-funded |
| Lab location | 1 site (Madison, United States) |
| Project ID | NIH-10817791 on NIH RePORTER |
What this research studies
This research examines the relationship between chronic epilepsy and accelerated brain aging using advanced imaging techniques like PET and MRI. It aims to identify specific biomarkers that indicate accelerated cognitive and brain aging in patients with chronic epilepsy compared to healthy individuals. By analyzing factors such as beta amyloid deposition and changes in brain structure and function, the study seeks to understand the impact of epilepsy on long-term brain health. Patients with chronic epilepsy may undergo neuroimaging assessments to help characterize these aging processes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with chronic focal epilepsy.
Not a fit: Patients without a diagnosis of epilepsy or those with acute, non-chronic forms of epilepsy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of cognitive decline in patients with chronic epilepsy.
How similar studies have performed: Previous research has shown promising results in understanding brain aging in other neurological conditions, suggesting potential for success in this area as well.
Where this research is happening
Madison, United States
- University of Wisconsin-Madison — Madison, United States (Active)
Researchers
- Principal investigator: Mcmillan, Alan Blair — University of Wisconsin-Madison
- Study coordinator: Mcmillan, Alan Blair
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.