NIH-funded research R01 grant

Integrating HIV, opioid use disorder, and infectious disease care in rural primary clinics

Official title: Integrating Addiction and Infectious Diseases Services into Primary Care in Rural Settings

Funded at Yale University · NIH-11332407 · Data updated 2026-11-12

A rural primary care project to help clinics better prevent HIV outbreaks and treat HIV, HCV, and opioid use disorder together.

More Primary Care research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionYale University
NIH-funded
Lab location1 site (New Haven, United States)
Project startAugust 1, 2021
Project endMay 31, 2027
Funding year2026
Award (this year)$1,063,519
NIH project number5R01DA054703-05
Project IDNIH-11332407 on NIH RePORTER

Who could benefit from this research

Could help

Adults in rural communities with HIV risk, HIV infection, hepatitis C co-infection, or opioid use disorder who receive care in primary clinics.

Less likely to help

Patients in areas without access to primary care clinics or those not engaged in HIV prevention or OUD treatment may not benefit.

What this research studies

In rural West Virginia, this project aims to make primary care clinics more capable of using medications for opioid use disorder, HIV treatment as prevention, and pre-exposure prophylaxis. The plan includes facilitated adoption of SET (screening, evaluation, treatment) processes for HIV/HCV/OUD, plus ongoing education and support. The effort uses NIATx strategies and Project ECHO to help clinics implement these practices with real-world patients. By strengthening primary care capacity, the study seeks to reduce HIV outbreaks and improve outcomes for people with HIV, hepatitis C, or OUD in rural communities.

Why it matters

Potential benefit: If successful, patients in rural areas could experience earlier HIV prevention and treatment, better management of opioid use disorder, and fewer outbreaks.

How similar studies have gone: Previous rural-adaptation efforts show that integrating HIV, HCV, and OUD care in primary settings can improve uptake of preventive and treatment services.

Where this research is happening

  • Yale University
    New Haven, United States
    Active

Researchers

  • Principal investigator: Altice, Frederick Lewis — Yale University
  • Study coordinator: Altice, Frederick Lewis

Related research

Other NIH-funded projects on the same topics.

  • Combining addiction and infectious disease services in rural primary care

    This study is looking to make it easier for people in rural West Virginia to get help for addiction and diseases like HIV and hepatitis C right at their local doctor's office, so they can receive the care they need in a friendly and supportive environment.

    NIH research Yale University · New Haven, United States · NIH-10864966

  • Improving access to treatment for alcohol use disorders through telemedicine.

    This study is looking to improve how doctors help people with alcohol use problems by using a telemedicine service that connects them with addiction specialists, making it easier for patients to get the right medications they need.

    NIH research Kaiser Foundation Research Institute · Oakland, UNITED STATES · NIH-10834075

  • HEARTS hypertension and diabetes care in Guatemala

    This grant tests how well the HEARTS primary care model works in Guatemala to improve blood pressure and blood sugar control for patients.

    NIH research University of Michigan at Ann Arbor · Ann Arbor, United States · NIH-11645315

  • Primary Care HEART-NET: boosting access to research in the Deep South

    A collaboration across three universities will build primary care research networks in Alabama, Arkansas, and Mississippi to improve access to care and help prevent and manage chronic diseases.

    NIH research University of Alabama at Birmingham · Birmingham, United States · NIH-11618658

  • Primary Care Bridge: Building Research in Diverse Geographic Settings

    A national network hub in New Mexico will connect rural clinics and communities to faster, more usable primary care research so patients in underserved areas can benefit from new evidence.

    NIH research University of New Mexico Health Scis Ctr · Albuquerque, United States · NIH-11618652

  • WREN: Expanding Research Capacity in Rural Primary Care Clinics

    A nationwide network in Wisconsin will strengthen rural primary care clinics to participate in real-world research and bring more clinical trials to communities.

    NIH research University of Wisconsin-Madison · Madison, United States · NIH-11618649

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.