Integrated treatment for people with both opioid and alcohol use disorders using GLP-1 medicines and standard therapies
Official title: Advancing Integrated Treatment for Co-Occurring Opioid and Alcohol Use Disorders: A Comprehensive Analysis of GLP-1 Receptor Agonists and Traditional Pharmacotherapies in Real-World Settings
Funded at Loyola University Chicago · NIH-11413630 · Data updated 2026-11-12
A real-world study of how combining GLP-1 receptor agonists with usual opioid and alcohol treatments works for people who have both disorders.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Loyola University Chicago NIH-funded |
| Lab location | 1 site (Maywood, United States) |
| Project start | September 25, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2026 |
| Award (this year) | $385,000 |
| NIH project number | 5R01AA031890-03 |
| Project ID | NIH-11413630 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with co‑occurring opioid and alcohol use disorders receiving real-world clinical care.
✕Less likely to help
Individuals without co‑occurring OUD and AUD or those not receiving integrated treatment in real-world settings are unlikely to benefit.
What this research studies
This project will use a large national health database to examine how people with co‑occurring opioid and alcohol problems respond to integrated treatment that includes GLP‑1 receptor agonists alongside standard medications for OUD and AUD. Researchers will look at outcomes like substance-use reduction, physical and mental health improvements, and how often detox services and drug tests are used. The study aims to identify which combinations work best in real clinical settings and what factors predict success. Findings could help clinicians tailor treatment plans to real‑world patient needs.
Why it matters
Potential benefit: If successful, patients with both OUD and AUD could receive more effective, real‑world treatment plans that reduce relapse and improve health.
How similar studies have gone: Prior studies show promise for GLP‑1 receptor agonists and integrated care, but real‑world, large-scale analyses in co‑occurring OUD/AUD are still developing.
Where this research is happening
-
Loyola University Chicago
Maywood, United States Active
Researchers
- Principal investigator: Qeadan, Fares — Loyola University Chicago
- Study coordinator: Qeadan, Fares
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.