Exploring treatments for patients with both opioid and alcohol use disorders

Advancing Integrated Treatment for Co-Occurring Opioid and Alcohol Use Disorders: A Comprehensive Analysis of GLP-1 Receptor Agonists and Traditional Pharmacotherapies in Real-World Settings

NIH-funded research Loyola University Chicago · NIH-11001407

This study is looking at how different treatment methods can help people who are dealing with both opioid and alcohol problems, to see which options work best for improving their overall health and recovery.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionLoyola University Chicago NIH-funded
Lab location1 site (Maywood, United States)
Project IDNIH-11001407 on NIH RePORTER

What this research studies

This research investigates how well integrated treatment approaches work for individuals struggling with both opioid and alcohol use disorders. By analyzing data from a large national database, the study aims to compare the effectiveness of traditional medications with newer options like GLP-1 receptor agonists. Patients will be monitored for improvements in substance use, physical health, and mental health outcomes. The goal is to find the best treatment strategies that can lead to better recovery results in real-world settings.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with both opioid use disorder and alcohol use disorder.

Not a fit: Patients who only have one of the disorders, either opioid use disorder or alcohol use disorder, may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to more effective treatment options for patients dealing with both opioid and alcohol use disorders.

How similar studies have performed: While there has been some research on treating these disorders separately, this integrated approach is relatively novel and has not been extensively tested in large-scale real-world settings.

Where this research is happening

Maywood, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.