Exploring treatments for patients with both opioid and alcohol use disorders
Official title: Advancing Integrated Treatment for Co-Occurring Opioid and Alcohol Use Disorders: A Comprehensive Analysis of GLP-1 Receptor Agonists and Traditional Pharmacotherapies in Real-World Settings
Funded at Loyola University Chicago · NIH-11001407 · Data updated 2026-11-12
This study is looking at how different treatment methods can help people who are dealing with both opioid and alcohol problems, to see which options work best for improving their overall health and recovery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Loyola University Chicago NIH-funded |
| Lab location | 1 site (Maywood, United States) |
| Project start | September 25, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $385,000 |
| NIH project number | 1R01AA031890-01 |
| Project ID | NIH-11001407 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals diagnosed with both opioid use disorder and alcohol use disorder.
✕Less likely to help
Patients who only have one of the disorders, either opioid use disorder or alcohol use disorder, may not benefit from this research.
What this research studies
This research investigates how well integrated treatment approaches work for individuals struggling with both opioid and alcohol use disorders. By analyzing data from a large national database, the study aims to compare the effectiveness of traditional medications with newer options like GLP-1 receptor agonists. Patients will be monitored for improvements in substance use, physical health, and mental health outcomes. The goal is to find the best treatment strategies that can lead to better recovery results in real-world settings.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatment options for patients dealing with both opioid and alcohol use disorders.
How similar studies have gone: While there has been some research on treating these disorders separately, this integrated approach is relatively novel and has not been extensively tested in large-scale real-world settings.
Where this research is happening
-
Loyola University Chicago
Maywood, United States Active
Researchers
- Principal investigator: Qeadan, Fares — Loyola University Chicago
- Study coordinator: Qeadan, Fares
Related research
Other NIH-funded projects on the same topics.
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Integrated treatment for people with both opioid and alcohol use disorders using GLP-1 medicines and standard therapies
A real-world study of how combining GLP-1 receptor agonists with usual opioid and alcohol treatments works for people who have both disorders.
-
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Integrated medication approaches for people with both opioid and alcohol use disorders
This project looks at how combining common addiction medicines and GLP-1 receptor agonists works for people who have both opioid and alcohol use problems using large-scale medical records.
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Understanding how veterans access care for alcohol use and behavioral health
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.