NIH-funded research R01 grant

Innovations in medications for opioid use disorder and access in Vancouver

Official title: Evaluating and informing innovations in medications for opioid use disorder modalities amidst the evolving illicit drug supply

Funded at Simon Fraser University · NIH-11296135 · Data updated 2026-11-12

A long-running study in Vancouver, Canada is testing new MOUD options and overdose-prevention strategies to see if they improve access, sticking with people who use drugs in the community.

More Opioid Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionSimon Fraser University
NIH-funded
Lab location1 site (Burnaby, Canada)
Project startJuly 15, 2026
Project endApril 30, 2031
Funding year2026
Award (this year)$507,566
NIH project number1R01DA062601-01A1
Project IDNIH-11296135 on NIH RePORTER

Who could benefit from this research

Could help

Adults in Vancouver who use drugs and are enrolled in or eligible for the VIDUS-Opioid cohort or similar community-recruited populations.

Less likely to help

Results may not directly benefit individuals who do not access MOUD or who do not participate in the cohort.

What this research studies

This project continues a nearly 30-year cohort study to understand how evolving illegal drugs and new MOUD options affect access, retention, and outcomes for people who use opioids in Vancouver. Researchers will follow participants over time, collecting data on medication use, housing, overdose events, and health outcomes while introducing or evaluating newer MOUD modalities and prevention strategies. The study builds on VIDUS-Opioid, a subset of a large, ongoing cohort, to capture real-world experiences in a setting hit hard by fentanyl and other adulterants. Findings are intended to guide clinicians and policymakers in tailoring treatments and harm-reduction approaches to current drug trends.

Why it matters

Potential benefit: If successful, the study could inform more effective MOUD options and overdose prevention strategies, improving retention in care and reducing overdoses for people who use opioids.

How similar studies have gone: The VIDUS cohort has provided longstanding, actionable insights; this continuation aims to adapt findings to evolving drug supplies and MOUD options.

Where this research is happening

  • Simon Fraser University
    Burnaby, Canada
    Active

Researchers

  • Principal investigator: Hayashi, Kanna — Simon Fraser University
  • Study coordinator: Hayashi, Kanna

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.