Improving RNA sequencing accuracy and efficiency
Official title: Re-Reading RNA to Obtain High Accuracy
Funded at Electronic Biosciences, INC. · NIH-10772963 · Data updated 2026-11-12
This study is working on a new way to read RNA that could make it faster and more accurate, helping doctors better understand and treat conditions related to RNA, which could be really helpful for patients.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Electronic Biosciences, INC. NIH-funded |
| Lab location | 1 site (San Diego, United States) |
| Project start | April 23, 2024 |
| Project end | January 22, 2026 |
| Funding year | 2024 |
| Award (this year) | $347,026 |
| NIH project number | 1R43HG012858-01A1 |
| Project ID | NIH-10772963 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve RNA abnormalities or require precise RNA analysis for diagnosis or treatment.
✕Less likely to help
Patients who do not have RNA-related conditions or who are not undergoing RNA sequencing may not benefit from this research.
What this research studies
This research focuses on developing a new technology for RNA sequencing that aims to achieve high accuracy and efficiency. By utilizing a nanopore reader, the project seeks to sequence single RNA molecules directly and repeatedly, which could eliminate the need for additional costly and time-consuming techniques. The approach also aims to allow for the sequencing of modified RNA bases, which is currently a limitation in existing methods. Patients may benefit from advancements in RNA sequencing that could lead to better understanding and treatment of various conditions related to RNA function.
Why it matters
Potential benefit: If successful, this research could lead to more accurate RNA sequencing, improving diagnostics and treatment options for patients with RNA-related conditions.
How similar studies have gone: Other research has shown promise in nanopore sequencing technologies, indicating potential for success in this novel approach.
Where this research is happening
-
Electronic Biosciences, INC.
San Diego, United States Active
Researchers
- Principal investigator: Schibel, Anna — Electronic Biosciences, INC.
- Study coordinator: Schibel, Anna
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.