Improving perioperative care for adults with opioid use disorder
Official title: Improving Perioperative Care for Patients with Opioid Use Disorder
Funded at University of Michigan at Ann Arbor · NIH-11386587 · Data updated 2026-11-12
A study to improve pain management and reduce opioid-related harms for adults with opioid use disorder who are having surgery.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Michigan at Ann Arbor NIH-funded |
| Lab location | 1 site (Ann Arbor, United States) |
| Project start | September 30, 2024 |
| Project end | July 31, 2029 |
| Funding year | 2026 |
| Award (this year) | $740,349 |
| NIH project number | 5R01DA058640-03 |
| Project ID | NIH-11386587 on NIH RePORTER |
Who could benefit from this research
✓Could help
Adults with opioid use disorder who are undergoing elective or non-elective surgeries at participating Michigan hospitals.
✕Less likely to help
Patients without opioid use disorder are not the target population for this care pathway.
What this research studies
This project will follow adults with opioid use disorder as they undergo common surgeries, collecting their reports on pain and opioid use after procedures. The team will use the findings to create a patient-centered perioperative care pathway that can be implemented across multiple Michigan hospitals. The goal is to tailor pain plans to reduce harms while ensuring effective pain control for this population. The work builds on Michigan’s existing opioid prescribing network to extend a coordinated approach to perioperative care.
Why it matters
Potential benefit: If successful, patients with opioid use disorder could experience better pain control with fewer opioid-related harms after surgery.
How similar studies have gone: Previous work has highlighted variation in perioperative outcomes; this study aims to translate that knowledge into a standardized care pathway, which is a logical next step with potential for meaningful impact.
Where this research is happening
-
University of Michigan at Ann Arbor
Ann Arbor, United States Active
Researchers
- Principal investigator: Bicket, Mark — University of Michigan at Ann Arbor
- Study coordinator: Bicket, Mark
Related research
Other NIH-funded projects on the same topics.
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Better surgery and pain care for people with opioid use disorder
This project will develop and try care pathways to help adults with opioid use disorder manage pain and reduce opioid-related harms around the time of surgery.
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Understanding how stopping medications for opioid use disorder after surgery affects recovery.
This study looks at what happens when people with opioid use disorder stop their medication after having surgery, and it aims to find out why this happens and how it affects their recovery, so we can help doctors better support these patients during and after their operations.
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Improving care for patients with opioid use disorder during surgery
This study is looking to improve how we manage pain for people with opioid use disorder who are having surgery, by understanding their specific challenges and finding better ways to help them feel comfortable after their procedures.
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Systems analysis to improve opioid use disorder care after jail release (SAIA-MOUD)
A program to help people with opioid use disorder get better, faster, and safer care after they leave jail.
-
Precise epigenetic drugs for opioid addiction
A tiny, targeted drug approach is being developed to help people with opioid use disorder by rewriting the epigenetic signals in the brain to reduce cravings and relapse risk.
-
Increasing Access to Medications for Opioid Use Disorder for Unhoused Montanans
This project helps unhoused people in Montana get life-saving medicines for opioid use disorder through clinics connected to syringe service programs, a nurse-led MOUD model, and peer support.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.