NIH-funded research R01 grant

Improving perioperative care for adults with opioid use disorder

Official title: Improving Perioperative Care for Patients with Opioid Use Disorder

Funded at University of Michigan at Ann Arbor · NIH-11386587 · Data updated 2026-11-12

A study to improve pain management and reduce opioid-related harms for adults with opioid use disorder who are having surgery.

More Opioid Use research and trials

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Michigan at Ann Arbor
NIH-funded
Lab location1 site (Ann Arbor, United States)
Project startSeptember 30, 2024
Project endJuly 31, 2029
Funding year2026
Award (this year)$740,349
NIH project number5R01DA058640-03
Project IDNIH-11386587 on NIH RePORTER

Who could benefit from this research

Could help

Adults with opioid use disorder who are undergoing elective or non-elective surgeries at participating Michigan hospitals.

Less likely to help

Patients without opioid use disorder are not the target population for this care pathway.

What this research studies

This project will follow adults with opioid use disorder as they undergo common surgeries, collecting their reports on pain and opioid use after procedures. The team will use the findings to create a patient-centered perioperative care pathway that can be implemented across multiple Michigan hospitals. The goal is to tailor pain plans to reduce harms while ensuring effective pain control for this population. The work builds on Michigan’s existing opioid prescribing network to extend a coordinated approach to perioperative care.

Why it matters

Potential benefit: If successful, patients with opioid use disorder could experience better pain control with fewer opioid-related harms after surgery.

How similar studies have gone: Previous work has highlighted variation in perioperative outcomes; this study aims to translate that knowledge into a standardized care pathway, which is a logical next step with potential for meaningful impact.

Where this research is happening

  • University of Michigan at Ann Arbor
    Ann Arbor, United States
    Active

Researchers

  • Principal investigator: Bicket, Mark — University of Michigan at Ann Arbor
  • Study coordinator: Bicket, Mark

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.